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Synthesis of a small library of nature-inspired xanthones and study of their an...
Resende, DISP; Pereira-Terra, P; Moreira, J; Freitas-Silva, J; Lemos, A; Gales, L; Pinto, E; Sousa, ME; Costa, PM; Pinto, MMMA series of thirteen xanthones 3-15 was prepared based on substitutional (appendage) diversity reactions. The series was structurally characterized based on their spectral data and HRMS, and the structures of xanthone derivatives 1, 7, and 8 were determined by single-crystal X-ray diffraction. This series, along with an in-house series of aminated xanthones 16-33, was tested for in-vitro antimicrobial activity ...
Date: 2020
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Origin: Repositório Aberto da Universidade do Porto
Breakthroughs in medicinal chemistry: New targets and mechanisms, New Drugs, Ne...
Mangoni, AA; Eynde, JJV; Jampilek, J; Hadjipavlou-Litina, D; Liu, H; Reynisson, J; Sousa, ME; Gomes, PAC; Prokai-Tatrai, K; Tuccinardi, T; Sabatier, JM
Date: 2019
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Origin: Repositório Aberto da Universidade do Porto
Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, ne...
Mangoni, AA; Guillou, C; Eynde, JJV; Hulme, C; Jampilek, J; Li, W; Prokai-Tatrai, K; Rautio, J; Collina, S; Tuccinardi, T; Sousa, ME; Sabatier, JM
Date: 2019
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Origin: Repositório Aberto da Universidade do Porto