13 documents found, page 1 of 2

Lower prevalence of congenital cytomegalovirus infection in Portugal: possible ...

Cytomegalovirus (CMV) is the most frequent cause of congenital infection all over the world. Its prevalence ranges from 0.2 to 2.2%. Transmission from children to their pregnant mothers is a well-known risk factor, particularly if they attend a childcare centre. This study aims to compare the prevalence of CMV congenital infection (CMV_CI) in Portugal (Lisbon) between two studies, performed respectively in 2019...

Gut Microbiota Diversity and C-Reactive Protein Are Predictors of Disease Sever...

The risk factors for coronavirus disease 2019 (COVID-19) severity are still poorly understood. Considering the pivotal role of the gut microbiota on host immune and inflammatory functions, we investigated the association between changes in the gut microbiota composition and the clinical severity of COVID-19. We conducted a multicenter cross-sectional study prospectively enrolling 115 COVID-19 patients categoriz...

Usefulness of Routine Fractional Flow Reserve for Clinical Management of Corona...

Importance: Approximately one-third of patients considered for coronary revascularization have diabetes, which is a major determinant of clinical outcomes, often influencing the choice of the revascularization strategy. The usefulness of fractional flow reserve (FFR) to guide treatment in this population is understudied and has been questioned. Objective: To evaluate the usefulness and rate of major adverse car...

Tratamento Sistémico do Eczema Atópico Grave em Idade Pediátrica

O eczema atópico (EA) é uma doença inflamatória crónica muito frequente em idade pediátrica. Na maioria dos casos o controlo clínico é alcançado com o recurso a hidratação adequada (emolientes) e a medicação tópica (corticosteroides tópicos, inibidores da calcineurina tópicos) embora exista um subgrupo de doentes com EA grave que não responde ao tratamento convencional ou que tem recidivas após a redução do mes...

Lawsonella clevelandensis as the causative agent of a breast abscess

Lawsonella clevelandensis is a Gram-stain-positive, partially acid-fast, anaerobic, being considered a new species within a new genus in the suborder Corynebacterineae. There are only a few cases reported worldwide. This is a fastidious microorganism, difficult to identify by conventional methods, leading to inappropriate treatments. The authors report a case of a 29-year-old woman with a 3-week evolution of a ...

Impact of Labor on Peripheral Blood Maternal T-Cell Subsets and on Regulatory T...

Labor is thought to positively influence immune system development in the offspring, but studies investigating the impact of different modes of delivery on maternal immune system cells are scarce. Therefore, the aim of this study was to investigate the effect of labor on maternal peripheral blood T-cell subsets and on the recently described regulatory T and B cells. METHODS: Cross-sectional study comparing the ...

Seroprevalence of Bordetella pertussis in healthcare workers in a Portuguese te...

Impact of Routine Fractional Flow Reserve on Management Decision and 1-Year Cli...

Background: Fractional flow reserve (FFR) is not firmly established as a guide to treatment in patients with acute coronary syndromes (ACS). Primary goals were to evaluate the impact of integrating FFR on management decisions and on clinical outcome of patients with ACS undergoing coronary angiography, as compared with patients with stable coronary artery disease. Methods and results: R3F (French FFR Registry) ...

Characterization of B cells in healthy pregnant women from late pregnancy to po...

BACKGROUND: B cells play a role in pregnancy due to their humoral and regulatory activities. To our knowledge, different maturational stages (from transitional to memory) of circulating B cell subsets have not yet been characterized (cell quantification and phenotype identification) in healthy pregnant women. Thus, the objective of our study was to characterize these subsets (as well as regulatory B cells) from...

Impact of Routine Fractional Flow Reserve Evaluation During Coronary Angiograph...

Penetration of fractional flow reserve (FFR) in clinical practice varies extensively, and the applicability of results from randomized trials is understudied. We describe the extent to which the information gained from routine FFR affects patient management strategy and clinical outcome. METHODS AND RESULTS: Nonselected patients undergoing coronary angiography, in which at least 1 lesion was interrogated by FFR...