15 documents found, page 1 of 2

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Adverse events related to etonogestrel implant: an old but still current issue?

Fernandes, João Paulo; Silva, Marcia; Sousa, Margarida; Bhikha, Jani; Moreira, Paula; Silva, Isabel

Introduction: In December 2019, in Portugal, a Direct Healthcare Professional Communication (DHPC) was approved regarding the subcutaneous implant of etonogestrel 68 mg. The genesis of this communication was based on reported cases of neurovascular injury and migration of the implant from the insertion site within the arm, or, in rare cases, into the pulmonary artery, possibly associated with deep or incorrect ...


Signatures and Consequences of Distributional Reinforcement Learning

Sousa, Margarida

"Learning to predict rewards is fundamental for adaptive behavior. Midbrain dopamine neurons (DANs) play a key role in such learning by signaling reward prediction errors (RPEs) that teach recipient circuits about expected rewards given current circumstances and actions [114]. However, the algo rithm that DANs are thought to provide a substrate for, temporal difference (TD) reinforcement learning (RL), learns t...


First insights of Portuguese primary schools’ fungal assessment: is indoor air ...

Pena, Pedro; Cervantes, Renata; Gomes, Bianca; Dias, Marta; Riesenberger, Bruna; Marques, Liliana; Sousa, Margarida; Viegas, Carla

The assessment of microbial indoor air quality in schools is vital for promoting student health. Portugal's regulations focus on commercial buildings (Ordinance nº 138-G/2021), neglecting standards for schools. Evidence suggests indoor/outdoor fungal ratio inadequacies in high-risk areas like schools. Objective: To assess fungal threshold adequacy set by the Portuguese ordinance in different sites of schools lo...


The Pediatric Perspective: A Comment on “Tuberculosis Screening of Ukrainian Re...

Barros, Marta; Sousa, Margarida; Barbosa, Luciana; Carvalho, Isabel

N/a.; N/a.

Date: 2023   |   Origin: Acta Médica Portuguesa

Bioinformatics study of expression from genomes of epidemiologically related MR...

Ribeiro, Miguel; Sousa, Margarida; Borges, Vítor; Gomes, João Paulo; Duarte, Sílvia; Isidro, Joana; Vieira, Luís; Torres, Carmen; Santos, Hugo

One of the most important livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) genetic lineages is the clonal complex (CC) 398, which can cause typical S. aureus-associated infections in people. In this work, whole-genome sequencing, RNA-sequencing, and gel-based comparative proteomics were applied to study the genetic characteristics of three MRSA CC398 isolates recovered from humans (str...


Um diálogo entre as práticas avaliativas de professores de ciências experimenta...

Sousa, Margarida

Este estudo pretende contribuir para melhorar o conhecimento sobre a avaliação das aprendizagens em salas de aula de ciências experimentais do 3.º ciclo do Ensino Básico (3.º CEB), envolvendo os alunos em atividades investigativas, decorrentes do trabalho colaborativo de professores. O contexto da escola justifica a sua realização numa mudança da cultura escolar, ao destacar a importância de elevar a integração...


Desenvolvimento de uma app para regulação das crianças com PEA entre os 3-6 ano...

Reis, Helena; Eusébio, Inês; Sousa, Margarida; Ferreira, Mariana; Pereira, Raquel

Introdução: Crianças com PEA são caracterizadas por apresentarem respostas atípicas aos estímulos sensoriais, tendo impacto no envolvimento e na participação funcional. O presente estudo descreve o processo de desenvolvimento de uma app com o intuito de ajudar as famílias a regular as crianças com PEA, entre os 3-6 anos, através da aplicação de estratégias sensoriais, para melhorar a participação nas rotinas di...

Date: 2021   |   Origin: IC-online

Regul-A: A Technological Application for Sensory Regulation of Children with Au...

Reis, Helena; Eusébio, Inês; Sousa, Margarida; Ferreira, Mariana; Pereira, Raquel; Dias, Sara; Reis, Catarina I.

Background: Sensory processing disorder is now recognised as a core feature of autism spectrum disorder that influences children’s adaptive behaviours, which, in turn, may interfere with their participation in life situations. This study describes the process of developing a technological platform, in the form of an app, to help families regulate children with ASD, aged 3–6 years old, by applying sensory strate...

Date: 2021   |   Origin: IC-online

Regul-A: Aplicação para Regular Crianças com PEA entre os 3-6 anos de idade, em...

Reis, Helena; Eusébio, Inês; Sousa, Margarida; Ferreira, Mariana; Pereira, Raquel; Dias, Sara; Reis, Catarina

Introdução: Crianças com PEA são caracterizadas por apresentarem respostas atípicas aos estímulos sensoriais, tendo impacto no envolvimento e na participação funcional. Objetivo: O presente estudo descreve o processo de desenvolvimento de uma app com o intuito de ajudar as famílias a regular as crianças com PEA, entre os 3-6 anos, através da aplicação de estratégias sensoriais, para melhorar a participação nas ...

Date: 2021   |   Origin: IC-online

MRSA CC398 recovered from wild boar harboring new SCCmec type IV J3 variant

Sousa, Margarida; Silva, Nuno; Borges, Vítor; Gomes, João P.; Vieira, Luís; Caniça, Manuela; Torres, Carmen; Igrejas, Gilberto; Poeta, Patrícia

A methicillin-resistant Staphylococcus aureus CC398 was recovered from a wild female boar (Sus scrofa) in the north of Portugal, in 2013 (Sousa et al. 2017). Whole genome sequencing (WGS) revealed this strain carries a new variant of a mecA-containing staphylococcal chromosomal gene cassette (SCCmec) type IV with an uncommon J3 region. WGS studies can facilitate surveillance and provide more detailed characteri...


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