15 documents found, page 1 of 2
Molecular investigation of ready-to-eat salads for Giardia duodenalis and Crypt...
Faria, Clarissa Perez; Pereira, Adelaide; Almeida, Daniela; Pinto, Miguel; Lourenço, Ágata; Sousa, Maria do CéuFoodborne outbreaks are often associated with the consumption of salads. However, published studies on the detection of foodborne pathogens in ready-to-eat salads are scarce. The aim of this study was to detect Giardia duodenalis and Cryptosporidium DNA in ready-to-eat salads, by applying techniques of molecular biology to study the frequency of contamination in salads. A total of 100 packages of ready-to-eat s...
Lipidome of extracellular vesicles from Giardia lamblia
Faria, Clarissa Perez; Ferreira, Bárbara; Lourenço, Ágata; Guerra, Inês Calado; Melo, Tânia; Domingues, Pedro; Domingues, Maria do Rosário MarquesExtracellular vesicles (EVs) (exossomes, microvesicles and apoptotic bodies) have been well acknowledged as mediators of intercellular communications in prokaryotes and eukaryotes. Lipids are essential molecular components of EVs but at the moment the knowledge about the lipid composition and the function of lipids in EVs is limited and as for now none lipidomic studies in Giardia EVs was described. Therefore, ...
Seroepidemiology study of Cytomegalovirus and Rubella in pregnant women in Luan...
Vueba, Amélia; Faria, Clarissa; Almendra, Ricardo; Santana, Paula; Sousa, Maria do CéuBackground: Both CMV and Rubella virus infections are associated with the risk of vertical transmission, fetal death or congenital malformations. In Angola, there are no reports of CMV and Rubella studies. Therefore, our objectives were to study the seroprevalence of anti-CMV and anti-Rubella antibodies in pregnant women of Luanda (Angola), identify the risk of primary infection during pregnancy and evaluate th...
Evaluation of the drinking water quality surveillance system in the metropolita...
Faria, Clarissa Pérez; Almendra, Ricardo; Dias, Gisele Silva; Santana, Paula; Sousa, Maria do Céu; Bessa de Freitas, MarceloThe present work evaluated the surveillance of the drinking water quality information system database and correlated the findings of the microbiological analysis with the distribution of intestinal protozoa from the metropolitan region of Rio de Janeiro. From the database, we obtained 1,654 georeferenced monitoring stations that were used in the analysis. The results indicate that the minimum number of samples ...
Prevalence of HIV and hepatitis B virus among pregnant women in Luanda (Angola)...
Vueba, Amélia Nkutxi; Almendra, Ricardo; Santana, Paula; Faria, Clarissa; Sousa, Maria do CéuHIV and HBV infections remain responsible for high rate of morbidity and mortality in many African Countries, affecting women and newborns. This study aims to analyze the spatial pattern of HIV and HBV infections in pregnant women in Luanda, Angola, and the statistical association between HIV and HBV and socio-economic characteristics, hygiene, and health status. Methods: Detection of anti-HIV antibodies (total...
Nanomedicines for the Delivery of Antimicrobial Peptides (AMPs)
Teixeira, Maria C.; Carbone, Claudia; Sousa, Maria do Céu; Espina, Marta; Garcia, Maria L.; Sanchez-Lopez, ElenaMicrobial infections are still among the major public health concerns since several yeasts and fungi, and other pathogenic microorganisms, are responsible for continuous growth of infections and drug resistance against bacteria. Antimicrobial resistance rate is fostering the need to develop new strategies against drug-resistant superbugs. Antimicrobial peptides (AMPs) are small peptide-based molecules of 5-100 ...
Serological prevalence of toxoplasmosis in pregnant women in Luanda (Angola): G...
Vueba, Amélia Nkutxi; Faria, Clarissa Perez; Almendra, Ricardo; Santana, Paula; Sousa, Maria do CéuWe report a study on toxoplasmosis in pregnant women in Luanda, Angola, determining the seroprevalence, geospatial distribution and its association with socio-economic features, dietary habits and hygiene and health conditions. Anti-Toxoplasma gondii IgG and IgM were quantified in serum samples of women attended at the Lucrecia Paim Maternity Hospital between May 2016 and August 2017. The IgG avidity test and q...
Giardia lamblia Decreases NF-κB p65RelA Protein Levels and Modulates LPS-Induce...
Faria, Clarissa Perez; Neves, Bruno Miguel; Lourenço, Ágata; Cruz, Maria Teresa; Martins, João D.; Silva, Ana; Pereira, Sónia; Sousa, Maria do CéuThe protozoan Giardia lamblia is the most common cause of parasitic gastrointestinal infection worldwide. The parasite developed sophisticated, yet not completely disclosed, mechanisms to escape immune system and growth in the intestine. To further understand the interaction of G. lamblia with host immune cells, we investigated the ability of parasites to modulate the canonical activation of mouse macrophages (...
Oral treatment with T6-loaded yeast cell wall particles reduces the parasitemia...
Scariot, Débora B.; Volpato, Hélito; Fernandes, Nilma S.; Lazarin-Bidóia, Danielle; Borges, Olga; Sousa, Maria do Céu; Rosa, Fernanda A.Yeast cell wall particles isolated from Saccharomyces cerevisiae (scYCWPs) have a rich constitution of β-glucan derived from the cell wall. After removing intracellular contents, β-glucan molecules are readily recognized by dectin-1 receptors, present on the cytoplasmic membrane surface of the mononuclear phagocytic cells and internalized. Leishmania spp. are obligate intracellular parasites; macrophages are it...
In vitro activities of glycoalkaloids from the Solanum lycocarpum against Leish...
Clementino, Leandro da Costa [UNESP]; Velásquez, Angela Maria Arenas [UNESP]; Passalacqua, Thais Gaban [UNESP]; de Almeida, Leticia [UNESP]Made available in DSpace on 2019-10-06T15:58:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-11-01. Added 1 bitstream(s) on 2019-10-09T18:35:02Z : No. of bitstreams: 1 S0102-695X2018000600673.pdf: 744468 bytes, checksum: 02f50876279d10d036ccab0e85453c1c (MD5); Leishmania infantum is an etiologic agent of visceral leishmaniasis. This disease is a neglected disease that can be fatal if not treated and a...