7 documents found, page 1 of 1

Early atypical malignant transformation of diffuse low-grade astrocytoma: The i...

Diffuse astrocytoma (WHO grade II) has classically been considered a slow growing tumour, typically affecting young adults, with tendency for late malignant conversion. We describe a case of early atypical malignant transformation of diffuse astrocytoma seventeen months after complete surgical removal, as an intraventricular high-grade glioma (HGG). Retrospective laboratory findings for the presence of IDH 1/2 ...

Poster: A Neuropsicologia no Hospital Dr. Nélio Mendonça: Passado,Presente e Fu...

Recomendações para o Diagnóstico e Tratamento do Adenocarcinoma Gástrico (Grupo...

Entire hemithorax irradiation for Masaoka stage IVa thymomas

Thymomas are rare neoplasms that have an indolent growth with a preferentially intra-thoracic dissemination pattern. Surgery is currently the standard treatment of thymomas; however radiotherapy is often used in an adjuvant setting due to a high sensitivity of these tumors to such treatment. Postoperative entire hemithoracic irradiation has been used in selected Masaoka stage IVa cases after complete surgical e...

Monoclonal antibodies. General approach and radioimmunotherapy.

Two major obstacles to systemic cancer therapy are the lack of specificity of therapeutic modalities and the intrapatient and interpatient heterogeneity of cancer cells. Because of their natural specificity, antibodies directed against tumor specific or tumor associated antigens have been raising interest in oncology. This article makes an overview of the basic principles of monoclonal antibodies, their limitat...

Gliosarcomas.

Gliosarcomas are rare tumors of the central nervous system with a poor prognosis. Histologically these tumors are characterized by an admixture of neoplastic glial cells and sarcomatous elements. Due to the scarcity of data in literature, the diagnosis is often missed and treatment is difficult. The authors report three cases of cerebral gliosarcomas and review the literature on this subject.; Gliosarcomas are ...

The role of external radiotherapy in the treatment of medullary carcinoma of th...

Medullary carcinoma of the thyroid represents 3 to 10% of all thyroid cancers. Surgery is the main treatment. External beam radiotherapy has a fundamental role in the treatment of residual disease following surgery, in cases of cervical node involvement, and in unresectable tumors. Between 1975 and 1993, 12 patients with medullary carcinoma of the thyroid were treated at the Department of Radiotherapy of the Po...