Recently, Organ-on-a-Chip (OoC) platforms have arisen as an increasingly relevant experimental tool for successfully replicating human physiology and disease. However, there is a lack of a standard technology to monitor the OoC parameters, especially in a non-invasive and label-free way. Photoacoustic (PA) systems can be considered an alternative and accurate assessment method for OoC platforms. PA systems comb...
Background: Surgical procedures present intricate challenges within healthcare delivery, often associated with higher risks of adverse events compared with non-surgical contexts. Patient and family engagement (PFE) throughout the perioperative journey is a possibility to enhance care quality, safety and patient-centredness. However, literature addressing PFE across the entirety of the perioperative journey rema...
A Core Measures Set (CMS) is an agreed standardized group of measures that should be assessed and reported in research for a specific condition or clinical area. This study undertook the development of a CMS for Patient Safety through a two-round, web-based Delphi consensus approach, in the context of the "Improving quality and patient SAFEty in surgical care through STandardisation and harmonization of periope...
By combining biomaterials, cell culture, and microfluidic technology, organ-on-a-chip (OoC) platforms have the ability to reproduce the physiological microenvironment of human organs. For this reason, these advanced microfluidic devices have been used to resemble various diseases and investigate novel treatments. In addition to the experimental assessment, numerical studies of biodevices have been performed aim...
INTRODUÇÃO: A maculopatia miópica na forma de neovascularização coroideia (mCNV) pode apresentar um impacto significativo na função visual, frequentemente em pacientes jovens ativos. O presente trabalho teve como objetivo descrever a biomecânica corneana em olhos míopes com histórico de mCNV tratados com anti-fator de crescimento endotelial vascular (VEGF) intravítreo e compará-la com os olhos contralaterais. O...
Introduction: Adverse events in health care affect 8% to 12% of patients admitted to hospitals in the European Union (EU), with surgical adverse events being the most common types reported. Aim: SAFEST project aims to enhance perioperative care quality and patient safety by establishing and implementing widely supported evidence-based perioperative patient safety practices to reduce surgical adverse events. Met...
INTRODUÇÃO: Existem poucos estudos publicados sobre doença do olho seco (DOS) no grupo etário pediátrico e os que existem foram realizados fora da Europa, onde os fatores genéticos e ambientais poderão ser diferentes. Além disso, o estudo da superfície ocular e, consequentemente, o diagnóstico da DOS cada vez mais tendem para métodos objetivos e padronizados. O objetivo primário desde trabalho foi de...
Introduction: Our objective was to compare the corneal biomechanics of myopes with non-myopes in a sample of Portuguese children. In addition, we sought to evaluate their habits and background as well as to assess the potential relationship of axial length and lens thickness with their corneal biomechanical properties. Methods: Observational cross-sectional study assessing healthy children (8 to 18 years old)...
INTRODUCTION: The prevalence of myopia is expected to increase significantly in the following decades. Moreover, axial myopia is associated with rhegmatogenous retinal detachment (RRD), a major cause of visual impairment in these patients. RRD develops after the dynamic interaction between the vitreous and the retina. Axial length (AL) is a well-described risk factor, but alone is insufficient to predict RRD. T...
Enquadramento: As quedas em contexto hospitalar são eventos adversos frequentes, sendo os medicamentos um importante fator contribuinte. Objetivo: Analisar notificações de queda de doentes internados e caracterizar o risco de queda com foco na terapia farmacológica, através da aplicação da Medication Fall Risk Score. Metodologia: Estudo observacional, descritivo e retrospetivo realizado num centro hospitalar po...