25 documents found, page 1 of 3

Prognostic Factors Associated with Disability in a Cohort of Neuromyelitis Opti...

Introduction: Neuromyelitis optica spectrum disorders (NMOSD) and MOG-associated disease (MOGAD) are an increasingly recognized group of demyelinating disorders of the central nervous system. Previous studies suggest that prognosis is predicted by older age at onset, number of relapses, the severity of the first attack and autoantibody status. Objective: To study prognostic factors associated with disability pr...

Synthesis of 6,8-diaminopurines via acid-induced cascade cyclization of 5-amino...

Inspired by the pharmacological interest generated by 6-substituted purine roscovitine for cancer treatment, 5-aminoimidazole-4-carboxamidine precursors containing a cyanamide unit were prepared by condensation of 5-amino-N-cyanoimidazole-4-carbimidoyl cyanides with a wide range of primary amines. When these amidine precursors were combined with acids, a fast cascade cyclization occurred at room temperature, af...

Diabetic Foot: Far Beyond a Superficial Wound

Relatório de Ensino Clínico - Integração à Vida Profissional

Em conformidade com o Guia de Funcionamento da Unidade Curricular (GFUC), o EC integra dois contextos de cuidados, designadamente: os Cuidados de Saúde Hospitalares (CSH) e os Cuidados de Saúde Primários (CSP). O contexto dos CSH decorreu no Serviço de Urgência Polivalente (SUP) do Centro Hospitalar Vila Nova de Gaia/Espinho (CHVNGE), já o contexto de CSP realizou-se na Unidade de Cuidados de Saúde Personalizad...

Fístula Gastro-Hepática na Doença Ulcerosa Péptica

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Standardization of in vitro digestibility and DIAAS method based on the static ...

Background: The FAO recommends the digestible indispensable amino acid score (DIAAS) as the measure for protein quality, for which the true ileal digestibility needs to be assessed in humans or pigs. However, due to high costs and ethical concerns, the FAO strongly encourages as well the development of validated in vitro methods, which complement the in vivo experiments. Method: Recently, an in vitro workflow, ...

Formulation Effects in the Antioxidant Activity of Extract from the Leaves of C...

Cymbopogon citratus DC (Stapf.) is a perennial grass and it is distributed around the world. It is used as a condiment for food and beverage flavouring in the form of infusions and decoctions of its dried leaves. Our previous studies have shown antioxidant, anti-inflammatory and gastroprotective activities for the infusion and its phenolic fractions. The aim of the present work was to develop oral dosage forms ...

Does the white coat influence satisfaction, trust and empathy in the doctor-pat...

Objectives To understand the influence of the white coat on patient satisfaction, opinions about medical clothing, perception about confidence, empathy and medical knowledge and the satisfaction and comfort level of physicians in consultation. Setting An interventional study was conducted with a representative sample of the population attending primary care in central Portugal. Participants The sample was compo...

Das categorias envolvidas na derivação de como assim de incredulidade no portug...

Guesser, Sousa e Kédochim (2019) argumentam que a expressão como assim de incredulidade (CAI) é um sintagma-wh de escopo alto nas sentenças, gerado diretamente na periferia esquerda, em [Spec,Int]. Neste squib, tomando a valoração de traços como uma estratégia feita derivacionalmente por meio de movimento (CHOMSKY, 2001; DONATI, 2008), fazemos uma análise dessa proposta considerando a hierarquia universal assum...

Internuclear Ophthalmoplegia: Manifestation of Clinically Isolated Syndrome in ...