Introduction: Synovial fluid investigation is the best alternative to diagnose prosthetic joint infection (PJI) before ade‐ quate microbiological/histology sampling during revision surgery. Although accurate preoperative diagnosis is certainly recommended, puncturing every patient before revision arthroplasty raises concerns about safety and feasibility issues especially in difficult to access joint (e.g., hip)...
Bone and joint infections represent a significant source of morbidity and mortality, often termed a “silent epidemic.” While native infections, such as septic arthritis and osteomyelitis, still persist, surgical site infections related to orthopedic implants have gained particular prominence due to their growing prevalence and complexity. These infections not only lead to substantial patient morbidity and morta...
Introduction: The loss of muscle mass is becoming a very common problem among critically ill patients and it’s also strongly related to their prognosis and quality of life after leaving the intensive care unit. The purpose of this study was to evaluate the loss of muscle mass in the first five days, since the patient is admitted to the intensive care unit, and if there is a relationship between this muscle wast...
Inflammatory reactions in the Bacillus Calmette-Guérin (BCG) inoculation scar site have been previously described, in association with viral infections. The inflammation of the scar in association with other vaccines has been described with the flu vaccine and, more recently, after the second dose of mRNA anti-SARS-CoV-2 vaccines (mRNA-1273 e BNT162b2), in two healthcare workers. We present the case of a 27-yea...
We report the case of a patient with a tibial shaft fracture occurring through a chronic posttraumatic osteomyelitis site with significant soft tissue defect. The bone and soft tissue reconstruction procedures are described with a cross-leg fasciocutaneous flap performed as a last resource after previous rotated muscle flap partial failure. Pre-operative CT angiography, to rule outaxial vessel damage and periph...
Introduction: Septic arthritis of a native joint represents a medical emergency. Drainage and effective antibiotic treatment are critical to avoid joint destruction and long-term impairment. The aim of this study was to evaluate epidemiological and clinical characteristics of patients with the diagnosis of septic arthritis to help establish local guidelines for empirical antibiotic treatment.Material and Method...
Background: Surgical site infection (SSI) prevalence in spinal instrumentation varies, depending on patient and surgery factors. This study aims to identify patient- and procedure-related factors associated with SSI after spinal instrumentation in 3 patient-specific groups: those undergoing surgery for degenerative, trauma-related, and pediatric deformity conditions. Methods: A case-control (1:2 ratio) analysis...
ntroduction: Septic arthritis of a native joint represents a medical emergency. Drainage and effective antibiotic treatment are critical to avoid joint destruction and long-term impairment. The aim of this study was to evaluate epidemiological and clinical characteristics of patients with the diagnosis of septic arthritis to help establish local guidelines for empirical antibiotic treatment. Material and method...
Background: Antibiotic-loaded spacers are often used during two-stage exchange for periprosthetic joint infections (PJIs) both for its mechanical properties and as a means of local antibiotic delivery. Purpose: The main goal of this study is to compare the efficacy of different options of antibiotic(s) in spacers concerning the rate of positive cultures at the second stage. Patients and Methods: We retrospectiv...
We describe a case of a patient with atrial fibrillation, anticoagulated with dabigatran, that developed severe knee skin necrosis in the setting of an acute periprosthetic knee infection, after initiating low-molecular-weight heparin. A wide range of etiology hypotheses was discussed within a multidisciplinary team. The complex approach consisted of treating the underlying infection, multiple types of soft-tis...