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Probe-based metagenomic pathogen detection: advancing laboratory capacity for c...

Ferreira, Rita; Coelho, Luís; Santos, João Dourado; Sobral, Daniel; Isidro, Joana; Mixão, Verónica; Pinto, Miguel; Nunes, Alexandra; Borrego, Maria José

Probe-based pathogen enrichment, followed by NGS, is a promising tool for complex diagnosis, overcoming traditional challenges of shotgun metagenomics, namely small microbial/human genetic material ratio and demanding computational resources. Here, we assessed the combined detection performance of two Illumina probe-based panels, the Respiratory and the Urinary Pathogen ID panels (RPIP and UPIP), using 99 clini...


Streamlining healthcare quality management with an web audit platform

Sousa, Rita; Esteves, Carlos; Abelha, António; Peixoto, Hugo

The quality management of services and products in health institutions covers several areas such as health education, access to information on prevention programs, disease tracking, professional training, availability of diagnostic equipment and therapeutic resources available, which demonstrates the importance that this management has to ensure an efficient administration. To ensure excellence, institutions ar...


The Digital Transition of Healthcare: A Pilot Experience

Amorim, Liliana; Moaris, Joana; Costa, Rui; Castanho, Teresa; Neves, Carolina; Sousa, Maria João; Sousa, Rita; Martins, Filipa; Domingues, Rui

The healthcare context is undergoing a significant transformation, facing a series of complex and unprecedented challenges. This transformation is triggered by accessibility constraints to healthcare services, increased expectations from patients and sing financial burdens. Rather than being seen as unsolvable obstacles, these challenges can be perceived as powerful stimuli, encouraging the search for innovativ...


Intratendinous Ganglion Cyst of the Extensor Indicis: A Case Report

Dias, João; Pinto, Irene; Costa, Diogo; Sousa, Rita; Pimenta, Tiago; Sapage, Rita

An intratendinous ganglion cyst is a very rare benign lesion with an unknown etiology. The clinical diagnosis can be difficult as patients may have mild symptoms or impaired hand functionality. Ultrasound and magnetic resonance imaging can differentiate a ganglion cyst from other soft-tissue tumors and tumor-like lesions and provide excellent information on the location of an intratendinous lesion to schedule s...


Prediction models applied to lung cancer using data mining

Sousa, Rita; Sousa, Regina; Peixoto, Hugo; Machado, José Manuel

Lung cancer is the most common cause of cancer death in men and the second leading cause of cancer death in women worldwide. Even though early detection of cancer can aid in the complete cure of the disease, the demand for techniques to detect the occurrence of cancer nodules at an early stage is increasing. Its cure rate and prediction are primarily dependent on early disease detection and diagnosis. Knowledge...


CLICTOUR - Roteiro para o turismo sustentável nas áreas protegidas do norte de ...

Sousa, Rita; Vieira, António; Silva, Luís; Ribeiro, Sara; Melo, Ana Duarte; Bento-Gonçalves, António; Viana, Artur; Gião, Cristiana Gomes

A indústria do turismo desempenha um papel de elevada relevância nas economias nacionais e regionais a nível global. Com o crescente interesse na visitação de áreas protegidas, muitas destas regiões, anteriormente intocadas, têm-se transformado em destinos turísticos de importância significativa e amplamente populares, atraindo um número elevado de visitantes anualmente. Ao mesmo tempo, várias áreas naturais e ...


Desenvolvimento de uma Matriz de Contabilidade Social para a análise do efeito ...

Gião, Cristiana Gomes; Sousa, Rita

Uma Matriz de Contabilidade Social (Social Accounting Matrix, SAM) pode ser utilizada para medir os impactos das mudanças climáticas no turismo e consequentemente na restante economia, através da análise das relações entre os diversos setores económicos e setores específicos. A SAM ajuda assim a identificar os setores e agentes mais afetados pelas mudanças e a magnitude dos seus impactos. No presente estudo opt...


Do wildfires burn tourism intentions? The case of Portugal

Cerejeira, João; Sousa, Rita; Bernardo, Carolina Tavares Silva; Bento-Gonçalves, António

Fire intensity and size incite visitation decrease and recreational losses, relevant tourism variables for European economies. As a result of climate change, this reality is becoming more evident. Due to significant gaps in analyzing the relationship between wildfires and tourism demand, this paper aims to explain how tourism demand reacts to wildfires in Portugal. We use a novel approach in these studies and e...


Bleb morphology of glaucoma drainage devices on magnetic resonance imaging

Correia Barão, Rafael; Berhanu, David; Matos, Diogo Bernardo; Barata, Andre; Sousa, Rita; Pinto, Luis

Purpose: To evaluate bleb morphology features of different glaucoma drainage devices (GDD) using magnetic resonance imaging (MRI). Materials and methods: Prospective cohort study of GDD and bleb morphology in consecutive glaucoma patients implanted with Ahmed Glaucoma Valve (AGV), Paul Glaucoma Implant (PGI), Baerveldt Glaucoma Implant (BGI) and Ahmed ClearPath (ACP) devices. Thirty-six eyes from 30 consecutive...


Orientações de consenso para a abordagem dos resultados alterados nos testes de...

Pedro, Amélia; Pacheco, Amália; Sousa, Rita; Mendinhos, Gustavo; Miranda, Mariana; Urzal, Cecília; Monteiro, Virgínia; Fraga, Teresa

O cancro do colo do útero (CCU) é globalmente um dos tipos de cancro mais comum em mulheres. O rastreio do CCU é indispensável para a deteção e tratamento de lesões neoplásicas cervicais que possam evoluir para neoplasia, com o objectivo de reduzir a incidência deste cancro. Nos últimos anos, têm ocorrido alterações que visam o aumento da eficácia do rastreio. Nomeadamente, o uso de teste de deteção do vírus do...


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