29 documents found, page 1 of 3
Copine 1 counteracts pneumolysin-induced plasma membrane damage caused by Strep...
Monteiro, João; Lima, Ricardo; Vale-Costa, Sílvia; Sousa, SandraStreptococcus pneumoniae causes pneumonia, meningitis, and sepsis, leading to millions of hospitalizations and deaths annually despite vaccination efforts. Understanding bacterial interaction with host cells is key to developing innovative therapies. Pneumolysin (PLY), a S. pneumoniae virulence factor, forms pores in the host cell plasma membrane (PM) to disrupt cellular integrity and promote bacterial dissemin...
As Estórias dentro da História: mapeando a nação no Museu da Revolução de João ...
Sousa, Sandra; Khan, Sheila PereiraMuseu da Revolução, o mais recente romance do escritor moçambicano João Paulo Borges Coelho, oferece ao leitor uma indagação sagaz e minuciosa sobre como lidar de uma forma reparadora com o passado moçambicano na sua relação com os legados da colonialidade no tempo da experiência da pós-colonialidade europeia e africana. Acompanhando o escritor neste exercício complexo e plural de reconhecimento de outras estór...
A Reparação da História e os Erros dos Seus Agentes em O Regresso de Júlia Mann...
Sousa, SandraÉ meu objetivo neste espaço analisar o mais recente livro de Teolinda Gersão, O Regresso de Júlia Mann a Paraty (2021), à luz do conceito de psicologia negra desenvolvido por Wade W. Nobles. Pretendo, assim, complexificar uma das questões centrais do romance, proferida por Sigmund Freud, o pai da psicanálise, tornado por Gersão (2021) em personagem-narrador fictícia: “será possível que sejamos incapazes de prog...
The Stories within History: Mapping the Nation in João Paulo Borges Coelho’s Mu...
Sousa, Sandra; Khan, SheilaMuseu da Revolução, the most recent novel by the Mozambican writer João Paulo Borges Coelho, offers the reader a shrewd and thorough question about how to deal in a thoughtful and restorative way with the Mozambican past in its relationship with the legacies of coloniality in post-coloniality. Following the writer in this complex and plural exercise of recognizing other stories, narratives and memories construc...
Immune and spermatogenesis-related loci are involved in the development of extr...
Cerván-Martín, Miriam; Tüttelmann, Frank; Lopes, Alexandra M.; Bossini-Castillo, Lara; Rivera-Egea, Rocío; Garrido, Nicolás; Lujan, SaturninoWe conducted a genome-wide association study in a large population of infertile men due to unexplained spermatogenic failure (SPGF). More than seven million genetic variants were analysed in 1,274 SPGF cases and 1,951 unaffected controls from two independent European cohorts. Two genomic regions were associated with the most severe histological pattern of SPGF, defined by Sertoli cell-only (SCO) phenotype, name...
Legacies of coloniality and racialization: Comparative Perspectives in Europe
Sousa, SandraThis study looks at two fiction writers—Chimamanda Ngozi Adichie and Djaimilia Pereira de Almeida—from two apparently distinct geographies, in order to argue for epistemological connections across African diasporic communities from different geographies. I will be reading, in particular, the issue of race and phenotype features portrayed in two of their books, That Hair (2015; published in translations by Tin H...
Management of Patients with Multiple Sclerosis During the COVID-19 Pandemics: A...
Miranda, Miguel; Sousa, Sandra; Pita, Fernando; Carmona, CátiaN/a.; N/a.
Devising another eternity: readings of Penthesilea in Vasco Graça Moura and Hél...
Sousa, SandraWestern literary and artistic tradition was particularly disdainful towards the representation of the epic battle between Achilles and Penthesilea, whose representation found no place in the Homeric poems. This amazon’s myth wasn’t depicted in any dramatic or epic text like some other classical tradition heroines such as Medea, Antigone and Helen were. Because the literary records of the myth are rare (in archa...
Discriminação positiva e discriminação negativa de pessoas com sexualidade não-...
Sousa, Sandra; Matos, Fátima; Mesquita, Rafael Fernandes; Henriques, Marco Ribeiro; Cardoso, AldrynTrabalhadores homossexuais são, constantemente, vítimas de discriminação no contexto laboral. Esta discriminação pode ser sentida, de forma negativa (quando a sua sexualidade prejudica a sua experiência na organização), ou de forma positiva (quando sua sexualidade contribui para a sua experiência na organização). Assim, o objetivo desse trabalho foi investigar os aspectos que caracterizam os dois tipos de discr...
Intronic variation of the SOHLH2 gene confers risk to male reproductive impairment
Cerván-Martín, Miriam; Suazo-Sánchez, M. Irene; Rivera-Egea, Rocío; Garrido, Nicolás; Luján, Saturnino; Romeu, Gema; Santos-Ribeiro, SamuelObjective: To evaluate whether SOHLH2 intronic variation contributes to the genetic predisposition to male infertility traits, including severe oligospermia (SO) and different nonobstructive azoospermia (NOA) clinical phenotypes. Design: Genetic association study. Setting: Not applicable. Patient(s): Five hundred five cases (455 infertile patients diagnosed with NOA and 50 with SO) and 1,050 healthy controls fr...