Purpose Burn wounds represent a significant challenge in medical care, particularly due to the complexity of dermal reconstruction. The use of autologous grafts as substitutes is the standard option, however, it may not be suitable to deep and extensive burns (1). An alternative approach involves employing artificial collagen-based dermal substitutes, which do not meet the full requirements of the dermis extrac...
This work studies the effect of different orthoses on preventing injuries in the ankle-foot joint. It was carried out using OpenSim and the available ankle-foot musculoskeletal model and AFO orthoses models. The motion situation assessed is related to placing the foot on the ground. It is also analyzed how a passive ankle-foot orthosis, muscles reflexes and muscle coactivation influence the risk of injury, name...
Ecological validity should be the cornerstone of any assessment of cognitive functioning. For this purpose, we have developed a preliminary study to test the Art Gallery Test (AGT) as an alternative to traditional neuropsychological testing. The AGT involves three visual search subtests displayed in a virtual reality (VR) art gallery, designed to assess visual attention within an ecologically valid setting. To ...
A Preschool Play Behavior Scale é um instrumento constituído por 18 itens que expressam diferentes tipos de comportamentos das crianças, em contexto de brincadeira livre com os pares, procurando diferenciar, em particular, tipos de comportamentos não-sociais. O presente estudo teve como objetivo traduzir e analisar a estrutura fatorial do instrumento e as suas características psicométricas. Sessenta educadoras ...
Porphyrins and some of its derivatives are well known and widely used as photosensitizers (PSs) for Photodynamic Therapy of Cancer (PDT). The present study regards the characterization and evaluation of a synthesized asymmetric porphyrin dye in solution to be used as PS for PDT. This molecule was also incorporated into biopolymeric films composed by chitosan, polyethylene glycol (PEG) and gelatin in order to ov...
In this work, a squaraine dye CS5 was characterized and evaluated for its potential in photodynamic therapy. The studies were performed in ethanol and also in a powdered biopolymer, in this case chitosan. Ground state absorption, absolute fluorescence quantum yields, fluorescence lifetimes, and transient absorption were determined in order to evaluate the advantage of adsorbing the dye onto a biopolymer. Severa...
Crack closure concept has been widely used to explain different issues of fatigue crack propagation. However, some authors have questioned the relevance of crack closure and have proposed alternative concepts. The main objective here is to check the effectiveness of crack closure concept by linking the contact of crack flanks with non-linear crack tip parameters. Accordingly, 3D-FE numerical models with and wit...