35 documents found, page 1 of 4
Cumulus cell DNA damage linked to fertilization success in females with an ovul...
Rodrigues, B; Sousa, V; Esteves, F; Vale-Fernandes, E; Costa, S; Sousa, D; Brandão, R; Leal, C; Pires, J; Gaivão, I; Teixeira, JP; Nogueira, AJAIntracytoplasmic sperm injection (ICSI) is a widely used technique in fertility centers. ICSI success depends on both nuclear and cytoplasmic oocyte maturation. Cumulus cells, which surround the oocytes, play a pivotal role in oocyte competence. However, the significance of DNA damage in cumulus cells as a marker of fertilization success remains largely unexplored. This study aims to investigate the relationshi...
Cytology applied to the animal field: fibroadenoma in female cat, discussion of...
Eliseu, C; Murça, I; Simões, I; Cassali, G; Sousa, V; Agapito, PBiological, genetic, histopathological, molecular, and morphological similarities have been made between human tumours and spontaneous neoplasms in pets. As such, spontaneous neoplasms in companion animals have been recognized as advantageous for the study of comparative oncobiology. Although it is difficult to estimate their prevalence and incidence, it is known that breast tumours are the most frequent type o...
Fine-needle aspiration cytology of axillary lymph node in patients with breast ...
Marques, Rita; Figueiredo, J P; Almeida, D; Martins, D; Sousa, V; Agapito, PIntroduction The breast is a glandular organ responsive to hormonal changes, therefore, according to the woman’s reproductive stage, the prevalence of different types of breast diseases varies. Breast cancer is the most prevalent (34,6%) in Portuguese women, its incidence has been rising and is most common in postmenopausal women (75%). However, younger women often present worst prognosis and more aggressive be...
Fibroadenoma and Phyllodes Tumor: Similarities and Differences – A Review
Costa, R; Estrada, T; Faria, C; Sousa, V; Agapito, PFibroadenoma and phyllodes tumor are the two main prototypes of breast fibroepithelial lesions. Fibroadenoma is the most common benign tumor in the female breast. The phyllodes tumor is rare and may have a benign, borderline or malignant character and in some cases may recur after excision and/or metastasize. Both neoplasms manifest clinically in the form of a breast lump. In their presence, the diagnostic appr...
A Comparative Study of Onychomycosis and Traumatic Toenail Onychodystrophy Derm...
Ramos Pinheiro, R; Dias Domingues, T; Sousa, V; Galhardas, C; Apetato, M; Lencastre, ABackground: Onychomycosis (OM) and traumatic onychodystrophy (OD) are common causes of toenail changes. A clinical diagnosis is often impossible without mycology. Dermoscopy is helpful in this setting but yet underexplored. Prospective comparative studies between OM and OD onychoscopic findings have not been previously performed. Objectives: We sought to determine distinguishing dermoscopic presentations of OM ...
Nephrotic Range Proteinuria in Renal Transplantation: Clinical and Histologic C...
Leal, R; Pinto, H; Galvão, A; Santos, L; Romãozinho, C; Macário, F; Alves, R; Pratas, J; Sousa, V; Marinho, C; Prado E Castro, L; Campos, M; Mota, AINTRODUCTION: There is a high incidence of nephrotic proteinuria in renal transplant recipients, which is an accurate predictor of graft loss. Despite this, its histologic correlates and prognostic implications are still not well characterized. We assessed the clinical and histological correlates of kidney transplantation patients with nephrotic range proteinuria. METHODS: We have retrospectively analyzed clini...
Fibrogenesis in Kidney Transplant: Dysfunction Progress Biomarkers
Costa, J S; Alves, R; Sousa, V; Marinho, C; Romãozinho, C; Santos, L; Macário, F; Pratas, J; Prado E Castro, L; Campos, M; Figueiredo, AFibrogenesis markers, such as alpha-actin (AA), CD163 (macrophages), and E-cadherin, have been studied as chronic kidney allograft injury (CAI) predictors, a major cause of allograft failure. OBJECTIVE: Investigate the value of these markers in predicting CAI and initiation of dialysis. MATERIALS AND METHODS: Retrospective analysis of 26 kidney allograft biopsies (from 22 patients with CAI) during 2 years, eval...
Polyomavirus Nephropathy: Ten-Year Experience
Costa, JS; Ferreira, E; Leal, R; Bota, N; Romãozinho, C; Sousa, V; Marinho, C; Santos, L; Macário, F; Alves, R; Pratas, J; Campos, M; Figueiredo, ABACKGROUND: Polyomavirus nephropathy (BKVN) is an important cause of chronic allograft dysfunction (CAD). Recipient determinants (male sex, white race, and older age), deceased donation, high-dose immunosuppression, diabetes, delayed graft function (DGF), cytomegalovirus infection, and acute rejection (AR) are risk factors. Reducing immunosuppression is the best strategy in BKVN. The objective of our study was ...
What Can We Do When All Collapses? Fatal Outcome of Collapsing Glomerulopathy a...
Pinto, H; Leal, R; Rodrigues, L; Santos, L; Romãozinho, C; Macário, F; Alves, R; Pratas, J; Sousa, V; Marinho, C; Prado E Castro, L; Costa, F; Campos, MNTRODUCTION: Collapsing glomerulopathy (CG) is a rare form of glomerular injury. Although commonly associated with human immunodeficiency virus (HIV) infection, it can occur in association with systemic lupus erythematosus (SLE). CASE REPORT: We present the case of a 50-year-old man, with chronic kidney disease secondary to focal and segmental glomerulosclerosis, who received a cadaveric kidney transplant in 20...
Dermoscopic and Reflectance Confocal Microscopic Presentation of Hailey‐Hailey ...
Oliveira, A; Arzberger, E; Pimentel, B; Sousa, V; Leal‐Filipe, PBackground/purpose: Hailey-Hailey disease is a rare inherited acantholytic skin disorder characterized by heterogeneous clinical presentation. Its differential diagnosis might be wide, including other genodermatoses, inflammatory, and infectious skin diseases. Although histopathology remains as diagnostic gold standard, noninvasive techniques such as dermoscopy and reflectance confocal microscopy may assist cli...