11 documents found, page 1 of 2
Abdominal Perfusion Pressure in Critically Ill Cirrhotic Patients: a Prospectiv...
Antunes Pereira, R; Esteves, A; Sousa Cardoso, F; Perdigoto, R; Marcelino, P; Saliba, FIn critical patients, abdominal perfusion pressure (APP) has been shown to correlate with outcome. However, data from cirrhotic patients is scarce. We aimed to characterize APP in critically ill cirrhotic patients, analyze the prevalence and risk factors of abdominal hypoperfusion (AhP) and outcomes. A prospective cohort study in a general ICU specialized in liver disease at a tertiary hospital center recruited...
Alcohol Consumption Post-Liver Transplantation: a Cross-Sectional Study
Chálim Rebelo, C; Félix, C; Sousa Cardoso, F; Bagulho, L; Sousa, M; Mendes, M; Glória, H; Mateus, É; Mega, I; Jara, M; Pinto Marques, H; Nolasco, FBackground: Listing patients with alcohol-associated liver disease (ALD) for liver transplant (LT) remains challenging especially due to the risk of alcohol resumption post-LT. We aimed to evaluate post-LT alcohol consumption at a Portuguese transplant center. Methods: We conducted a cross-sectional study including LT recipients from 2019 at Curry Cabral Hospital, Lisbon, Portugal. A pretested survey and a vali...
Exploring Nitrogen-Functionalized Graphene Composites for Urinary Catheter Appl...
Rita Teixeira dos Santos; Luciana Gomes; Vieira, R; Sousa Cardoso, F; Soares, SGP; Filipe MergulhãoGraphene has been broadly studied, particularly for the fabrication of biomedical devices, owing to its physicochemical and antimicrobial properties. In this study, the antibiofilm efficacy of graphene nanoplatelet (GNP)-based composites as coatings for urinary catheters (UCs) was investigated. GNPs were functionalized with nitrogen (N-GNP) and incorporated into a polydimethylsiloxane (PDMS) matrix. The resulti...
How do Graphene Composite Surfaces Affect the Development and Structure of Mari...
Maria João Romeu; Luciana Gomes; Sousa Cardoso, F; Morais, J; Vitor Vasconcelos; Whitehead, KA; Pereira, MFR; Soares, OSGP; Filipe MergulhãoThe progress of nanotechnology has prompted the development of novel marine antifouling coatings. In this study, the influence of a pristine graphene nanoplatelet (GNP)-modified surface in cyanobacterial biofilm formation was evaluated over a long-term assay using an in vitro platform which mimics the hydrodynamic conditions that prevail in real marine environments. Surface characterization by Optical Profilome...
Positive Fluid Balance Was Associated with Mortality in Patients with Acute-on-...
Sousa Cardoso, F; Pereira, R; Laranjo, A; Gamelas, V; Bagulho, L; Germano, N; Karvellas, CPurpose: We aimed to study the effect of FB in the outcomes of critically-ill patients with cirrhosis. Materials: Retrospective analysis of all adult consecutive admissions of patients with cirrhosis and organ failures to the Intensive Care Unit (ICU) at Curry Cabral Hospital (Lisbon, Portugal) and University of Alberta Hospital (Edmonton, Canada) on 08/2013-08/2017. Primary exposure was FB at 3 and 7 days post...
Optic Nerve Sheath Diameter in Acute Liver Failure: A Prospective Cohort Study
Sousa Cardoso, F; Pereira, R; Moreno, R; Karvellas, C; Germano, NIntroduction: Acute liver failure (ALF) is a rare disease that may lead to cerebral edema and death. An increased optic nerve sheath diameter (ONSD) may reflect an early increase in intracranial pressure. We assessed the feasibility and safety of the ONSD measurement and its association with outcomes in patients with ALF. Methods: This was an open-label prospective cohort study including adult patients with ALF...
Acute-on-Chronic Liver Failure Syndrome - Clinical Results from an Intensive Ca...
Pereira, R; Bagulho, L; Sousa Cardoso, FObjective: To characterize a cohort of acute-on-chronic liver failure patients in Intensive Care and to analyze the all-cause 28-day mortality risk factors assessed at ICU admission and day 3. Methods: This was a retrospective cohort study of consecutive patients admitted to the intensive care unit between March 2013 and December 2016. Results: Seventy-one patients were included. The median age was 59 (51 - 64)...
Lactate and Number of Organ Failures Predict Intensive Care Unit Mortality in P...
Sousa Cardoso, F; Abraldes, J; Sy, E; Ronco, JJ; Bagulho, L; Mcphail, M; Karvellas, CBackground and aims: Patients with acute-on-chronic liver failure (ACLF) have high mortality rates. Most prognostic scores were not developed for the intensive care unit (ICU) setting. We aimed to improve risk stratification for patients with ACLF in the ICU. Methods: A training set with 240 patients with cirrhosis and organ failures (Chronic Liver Failure Sequential Organ Failure Assessment score [CLIF-SOFA]) ...
Time of Admission to Intensive Care Unit, Strained Capacity, and Mortality: a R...
Sousa Cardoso, F; Germano, N; Bento, L; Fortuna, PPurpose: We sought to study the association between afterhours ICU admission and ICU mortality considering measures of strained ICU capacity. Materials and methods: Retrospective analysis of 4141 admissions to 2 ICUs in Lisbon, Portugal (06/2016-06/2018). Primary exposure was ICU admission on 20:00 h-07:59 h. Primary outcome was ICU mortality. Measures of strained ICU capacity were: bed occupancy rate ≥ 90% and...
Respiratory Complications Before and After Liver Transplant
Sousa Cardoso, F; Karvellas, CRespiratory complications before and after liver transplant are common, diverse, and potentially have a negative impact on patient outcomes. In this review, we discuss the most frequent respiratory conditions that patients may develop in the perioperative period. Their prevention and/or treatment may help to maximize the benefit these patients may derive from liver transplant. This review examines diagnostic an...