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A Farmacopeia Portuguesa e a Farmacopeia Europeia: Revisão histórica e sua impo...

Conceição, Jaime; Pita, João Rui; Cabral-Marques, Helena Maria; Sousa Lobo, José Manuel


Intranasal delivery of nanostructured lipid carriers, solid lipid nanoparticles...

Costa, Cláudia Pina; Moreira, João Nuno; Sousa Lobo, José Manuel; Silva, Ana Catarina

The management of the central nervous system (CNS) disorders is challenging, due to the need of drugs to cross the blood‒brain barrier (BBB) and reach the brain. Among the various strategies that have been studied to circumvent this challenge, the use of the intranasal route to transport drugs from the nose directly to the brain has been showing promising results. In addition, the encapsulation of the drugs in ...


Vaginal Preparations: Yesterday, Today and Tomorrow

Correia, Armanda do Carmo Ferreira Abreu de Sousa; Silva, Ana Catarina; Sousa Lobo, José Manuel

Pharmaceutical preparations for vaginal use have been applied since Antiquity to treat vaginal diseases. The local action of drugs administered in the vagina promotes the effectiveness of treatments and reduces toxic effects. In addition, some small lipophilic molecules are able to permeate the vaginal mucosa and are absorbed systemically. The possibility of systemic absorption through the vagina highlights it ...


Development of a platform to align education and practice: bridging Academia an...

Alves da Costa, Filipa; Martins, Ana Paula; Veiga, Francisco; Ramalhinho, Isabel; Sousa Lobo, José Manuel; Rodrigues, Luís; Granadeiro, Luiza

Limited fitness for practice may result from a mismatch between education and practice. Aiming to meet the common interests of academics and practitioners, the Portuguese Pharmaceutical Society (PPS) developed the Education and Practice Platform (EPP). The EPP includes one representative from each pharmacy faculty, and all Councils of Speciality Boards of Practice. Brainstorming with involved parties enabled sh...


Double optimization of rivastigmine-loaded Nanostructured Lipid Carriers (NLC) ...

Cunha, Sara; Costa, Cláudia Pina; Loureiro, Joana A.; Alves, Jorge; Peixoto, Andreia F.; Forbes, Ben; Sousa Lobo, José Manuel; Silva, Ana Catarina

Rivastigmine is a drug commonly used in the management of Alzheimer's disease that shows bioavailability problems. To overcome this, the use of nanosystems, such as nanostructured lipid carriers (NLC), administered through alternative routes seems promising. In this work, we performed a double optimization of a rivastigmine-loaded NLC formulation for direct drug delivery from the nose to the brain using the qua...


Development of a platform to align education and practice: bridging academia an...

Alves da Costa, Filipa; Martins, Ana Paula; Veiga, Francisco; Ramalhinho, Isabel; Sousa Lobo, José Manuel; Rodrigues, Luís; Granadeiro, Luiza

Limited fitness for practice may result from a mismatch between education and practice. Aiming to meet the common interests of academics and practitioners, the Portuguese Pharmaceutical Society (PPS) developed the Education and Practice Platform (EPP). The EPP includes one representative from each pharmacy faculty, and all Councils of Speciality Boards of Practice. Brainstorming with involved parties enabled sh...


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