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Glycopeptide-based supramolecular hydrogels induce differentiation of adipose s...

Castro, Vânia Isabel Baptista; Araújo, Ana Rita Rodrigues; Duarte, Filipa; Sousa-Franco, António; Reis, R. L.; Pashkuleva, I.; Pires, R. A.

We applied a bottom-up approach to develop biofunctional supramolecular hydrogels from an aromatic glycodipeptide. The self-assembly of the glycopeptide was induced by either temperature manipulation (heatingâ cooling cycle) or solvent (DMSO to water) switch. The solâ gel transition was salt-triggered in cell culture media and resulted in gels with the same chemical compositions but different mechanical propert...


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