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Nationwide study of drug resistance mutations in HIV-1 infected individuals und...

Santos-Pereira, Ana; Triunfante, Vera; Araújo, Pedro M. M.; Martins, Joana; Soares, Helena; Poveda, Eva; Souto, Bernardino; Osório, Nuno S.

The success of antiretroviral treatment (ART) is threatened by the emergence of drug resistance mutations (DRM). Since Brazil presents the largest number of people living with HIV (PLWH) in South America we aimed at understanding the dynamics of DRM in this country. We analyzed a total of 20,226 HIV-1 sequences collected from PLWH undergoing ART between 2008–2017. Results show a mild decline of DRM over the yea...


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