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Correction: Jose et al. Transferrin-Conjugated Docetaxel-PLGA Nanoparticles for...

Jose, Sajan; Cinu, Thomas A; Sebastian, Rosmy; Shoja, M H; Aleykutty, N A; Durazzo, Alessandra; Lucarini, Massimo; Santini, Antonello; Souto, E. B.

In the original publication [...].


Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An inn...

Andreani, T.; Dias-Ferreira, J.; Fangueiro, J. F.; Souza, A. L.R. [UNESP]; Kiill, C. P. [UNESP]; Gremião, M. P.D. [UNESP]; García, M. L.; Silva, A. M.

Made available in DSpace on 2020-12-12T01:21:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-05-01; Fundação para a Ciência e a Tecnologia; Federación Española de Enfermedades Raras; Sunscreens have been employed on daily skin care for centuries. Their role in protecting the skin from sun damage, avoiding accelerated photoaging and even limiting the risk of development of skin cancer is unquestionable...

Date: 2020   |   Origin: Oasisbr

d-α-tocopherol nanoemulsions: Size properties, rheological behavior, surface te...

Teixeira, M. C.; Severino, P.; Andreani, T.; Boonme, P.; Santini, A.; Silva, A. M.; Souto, E. B.

The aim of this study was the assessment of the physicochemical stability of d-α-tocopherol formulated in medium chain triglyceride nanoemulsions, stabilized with Tween®80 and Lipoid®S75 as surfactant and co-surfactant, respectively. d-α-tocopherol was selected as active ingredient because of its well-recognized interesting anti-oxidant properties (such as radical scavenger) for food and pharmaceutical industri...


Ibuprofen nanocrystals developed by 22 factorial design experiment: A new appro...

Fernandes, A. R.; Ferreira, N. R.; Fangueiro, J. F.; Santos, A. C.; Veiga, F. J.; Cabral, C.; Silva, A. M.; Souto, E. B.

The reduction of the particle size of drugs of pharmaceutical interest down to the nano-sized range has dramatically changed their physicochemical properties. The greatest disadvantage of nanocrystals is their inherent instability, due to the risk of crystal growth. Thus, the selection of an appropriate stabilizer is crucial to obtain long-term physicochemically stable nanocrystals. High pressure homogenization...


Compatibility study of paracetamol, chlorpheniramine maleate and phenylephrine ...

de Oliveira, G. G. G.; Feitosa, A.; Loureiro, K.; Fernandes, A. R.; Souto, E. B.; Severino, P.

Paracetamol (PAR), phenylephrine hydrochloride (PHE) and chlorpheniramine maleate (CPM) are commonly used in clinical practice as antipyretic and analgesic drugs to ameliorate pain and fever in cold and flu conditions. The present work describes the use of thermal analysis for the characterization of the physicochemical compatibility between drugs and excipients during the development of solid dosage forms. The...


Lipid nanoparticles (SLN (R), NLC (R)) for cutaneous drug delivery

Souto, E. B.; Almeida, A. J.; Mueller, R. H.

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) are new drug delivery systems composed of physiological lipid materials and surfactants accepted by regulatory authorities for application in cutaneous drug delivery, i.e., topical, d


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