Encontrados 17 documentos, a visualizar página 1 de 2
Prevalence of hepatitis B and D virus infection in a district of Mato Grosso, b...
Antonio Ferreira-Junior,Paulo; de-Oliveira,Elaine Cristina; Martin,Thamires Oliveira Gasquez; Rodrigues Alves-Junior,Eduardo; Silva,Lucas José daAbstract INTRODUCTION: Brazil’s western Amazon basin has the highest prevalence of hepatitis B virus (HBV) infection in the country. Coinfection with hepatitis D virus (HDV) is also endemic. To estimate the prevalence of HBV and HDV markers in a population inhabiting the northwest portion of Mato Grosso state in the western Amazon. METHODS: We performed a cross-sectional study of the seroprevalence of antibodie...
Syphilis in pregnant women and congenital syphilis: spatial pattern and relatio...
Oliveira,Leila Regina de; Santos,Emerson Soares dos; Souto,Francisco José DutraAbstract INTRODUCTION: The increasing incidence of syphilis among pregnant women (PS) and congenital syphilis (CS) has negatively affected maternal-child health in Brazil. The spatial approach to diseases with social indicators improves knowledge of health situations. Herein, we aimed to evaluate the spatiotemporal distribution of incidences, identify the priority areas for infection control actions, and analyz...
Expression of annexin-A1 in blood and tissue leukocytes of leprosy patients
Ribeiro,Afonso Bezerra; Caloi,Caroline Marques; Pimenta,Silvia Thais Sá; Seshayyan,Sudha; Govindarajulu,Srinivas; Souto,Francisco José DutraAbstract INTRODUCTION In leprosy, immune system mediators that regulate the infectious process act in a complex manner and can lead to several clinical outcomes. To understand the behavior of these mediators we quantified the expression of annexin-A1 (ANXA1) in the peripheral blood and plasma as well as tissue leukocytes in all clinical forms of leprosy and compared with healthy controls. METHODS Seventy health...
Vacinação universal contra hepatite A no Brasil: análise da cobertura vacinal e...
Brito,Wagner Izidoro de; Souto,Francisco José DutraRESUMO: Introdução: Em 2014, o Brasil introduziu programa de imunização universal contra o vírus da hepatite A (HAV) para crianças no segundo ano de vida, por meio de dose única da vacina de vírus inativado. Este estudo teve como objetivo avaliar a cobertura vacinal (CV) contra o HAV no Brasil, diante da incidência de casos notificados cinco anos após a implantação do programa. Metodologia: Dados secundários fo...
Hepatitis C disease burden and strategies for elimination by 2030 in Brazil. A ...
Benzaken,Adele Schwartz; Girade,Renato; Catapan,Elisa; Pereira,Gerson Fernando Mendes; Almeida,Elton Carlos de; Vivaldini,Simone; Fernandes,NeideABSTRACT Introduction and aim: Hepatitis C is a key challenge to public health in Brazil. The objective of this paper was to describe the Brazilian strategy for hepatitis C to meet the 2030 elimination goal proposed by World Health Organization (WHO). Methods: A mathematical modeling approach was used to estimate the current HCV-infected Brazilian population, and to evaluate the relative costs of two different ...
Effectiveness of first-wave protease inhibitors in hepatitis C virus genotype 1...
Lobato,Cirley Maria de Oliveira; Balassiano,Natalia; Hyppolito,Elodie Bomfim; Sanchez-Lermen,Rafaela Liz Pellegrim; Signorelli,Izabelle VenturiniAbstract INTRODUCTION: In 2013, combination therapy using peginterferon, ribavirin, and boceprevir or telaprevir was introduced to treat hepatitis C virus genotype 1 infection in Brazil. The effectiveness of this therapy in four Brazilian regions was evaluated. METHODS: Clinical and virological data were obtained from patients of public health institutions in five cities, including sustained virological respons...
Initial evaluation of universal immunization with a single dose against hepatit...
Brito,Wagner Izidoro de; Alves-Junior,Eduardo Rodrigues; Oliveira,Rode Martinho de; Souto,Francisco José DutraABSTRACT Vaccination against the hepatitis A virus (HAV) administered in two doses has been used effectively in universal child immunization programs in several countries. A single-dose vaccination was adopted in some low-income countries in an attempt to reduce costs without losing effectiveness. In 2014, single-dose universal vaccination was introduced in Brazil for children aged two years. Since such strateg...
Distribution of hepatitis B infection in Brazil: the epidemiological situation ...
Souto,Francisco José DutraAbstract Brazil was formerly considered a country with intermediate hepatitis B endemicity, with large heterogeneity between Brazilian regions and areas of high prevalence, especially in the Amazon basin. Systematic vaccination of children was initiated in 1998. Between 2004 and 2009, a large population-based study reported decreased prevalence in all regions of Brazil. This review analyzed the current hepatiti...
Observational descriptive study of cutaneous manifestations in patients from Ma...
Rostey,Renato Roberto Liberato; Souto,Francisco José DutraAbstract: BACKGROUND: Extrahepatic manifestations are seen in association with chronic infection by hepatitis B or C virus including cutaneous disorders. The frequency of these findings seems to vary among different places and reports. There is a lack of information about this issue in Brazil. OBJECTIVES: To estimate the prevalence of cutaneous findings affecting HBV or HCV carriers from a reference outpatient ...
Incapacidade pós-tratamento em pacientes hansenianos em Várzea Grande, Estado d...
Ramos,José María Hernández; Souto,Francisco José DutraINTRODUÇÃO: A hanseníase é um importante problema de saúde pública. O Brasil responde por mais de 90% dos casos do continente americano. Aproximadamente, 23% dos pacientes hansenianos apresentam algum tipo de incapacidade após a alta. MÉTODOS: Neste estudo, estimou-se a prevalência das incapacidades em 169 pacientes (94 homens e 75 mulheres) com qualquer das formas clínicas de hanseníase no município de Várzea ...