5 documents found, page 1 of 1
MHC Variants Associated With Symptomatic Versus Asymptomatic SARS-CoV-2 Infecti...
Castelli, Erick C. [UNESP]; de Castro, Mateus V.; Naslavsky, Michel S.; Scliar, Marilia O.; Silva, Nayane S. B. [UNESP]; Andrade, Heloisa S. [UNESP]Made available in DSpace on 2022-04-29T08:46:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-28; Center for Information Technology; Center for Scientific Review; National Institutes of Health; Office of Extramural Research, National Institutes of Health; Office of Research Infrastructure Programs, National Institutes of Health; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fu...
HLA-G genetic diversity and evolutive aspects in worldwide populations
Castelli, Erick C. [UNESP]; de Almeida, Bibiana S.; Muniz, Yara C. N.; Silva, Nayane S. B. [UNESP]; Passos, Marília R. S. [UNESP]Made available in DSpace on 2022-04-29T08:46:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-01; HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents substantial nucleotide variability in its regulatory regions. However, it encodes a limited number of proteins compared to classical HLA class I genes. We characterized the HLA-G genetic variability in 4640 individuals from 88 di...
KIR2DL4 genetic diversity in a Brazilian population sample: implications for tr...
Weiss, Emiliana [UNESP]; Andrade, Heloisa S. [UNESP]; Lara, Juliana Rodrigues [UNESP]; Souza, Andreia S. [UNESP]; Paz, Michelle A. [UNESP]Made available in DSpace on 2021-06-25T10:53:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); KIR2DL4 is an important immune modulator expressed in natural killer cells; HLA-G is its main ligand. We have characterized the KIR2DL4 genetic diversity by considering the promoter, all exons, and all introns in a highly admixed Brazilian p...
Hla-C genetic diversity and evolutionary insights in two samples from Brazil an...
Souza, Andreia S. [UNESP]; Sonon, Paulin; Paz, Michelle A. [UNESP]; Tokplonou, Léonidas; Lima, Thálitta H. A. [UNESP]; Porto, Iane O. P. [UNESP]Made available in DSpace on 2020-12-12T02:19:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Human leukocyte antigen-C (HLA-C) is a classical HLA class I molecule that binds and presents peptides to cytotoxic T lymphocytes in the cell surface. HLA-C has a dual function because it also interacts with Killer-cell immunoglobulin-like receptors (KIR) receptors expressed in natural killer and T cell...
EVALUATION OF THE HLA-F VARIABILITY IN BRAZIL BY NEXT GENERATION SEQUENCING
Castelli, Erick C. [UNESP]; Lima, Thalitta H. A. [UNESP]; Buttura, Renato V. [UNESP]; Paz, Michelle A. [UNESP]; Porto, Iane O. P. [UNESP]Made available in DSpace on 2018-11-26T15:28:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-01-01; UNESP Univ Estadual Paulista, Botucatu, SP, Brazil; Univ Sao Paulo, Sch Med Ribeirao Preto, Ribeirao Preto, SP, Brazil; Fac Filosofia Ciencias & Letras Ribeirao Preto, Ribeirao Preto, SP, Brazil; UNESP Univ Estadual Paulista, Botucatu, SP, Brazil