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The alpha-lipoic acid improves survival and prevents irinotecan-induced inflamm...

Costa, Daniely V. S.; Costa, Deiziane V. S.; Sousa, Caren N. S.; Silva, Angeline M. H. P.; Medeiros, Ingridy S.; Martins, Dainesy S.

Irinotecan, an anticancer drug, induces diarrhea and intestinal inflammation, resulting in an increase in the cost of care and in treatment delays. In this study, we investigated whether alpha-lipoic acid (α-LA) could improve irinotecan-mediated intestinal inflammation, diarrhea and dysmotility. Intestinal mucositis was induced by irinotecan injection (75 mg/kg, i.p., for 4 days) in Swiss mice. α-LA (50, 100 or...

Date: 2021   |   Origin: Oasisbr

Structure of a lectin from Canavalia gladiata seeds: new structural insights fo...

Delatorre, Plinio; Rocha, Bruno A. M.; Souza, Emmanuel P.; Oliveira, Taiana M.; Bezerra, Gustavo A.; Moreno, Frederico B. M. B.; Freitas, Beatriz T.

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2014-02-26T17:00:06Z No. of bitstreams: 1 WOS000249301900001.pdf: 1962990 bytes, checksum: 0c65e4a3836e97a4f347eb45bda09f6a (MD5); Made available in DSpace on 2014-02-26T17:00:07Z (GMT). No. of bitstreams: 1 WOS000249301900001.pdf: 1962990 bytes, checksum: 0c65e4a3836e97a4f347eb45bda09f6a (MD5) Previous issue date: 2007-08-02; Submitted by Vitor Si...

Date: 2014   |   Origin: Oasisbr

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