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The thyroid hormone receptor β-selective agonist GC-1 does not affect tolerance...

Gonçalves, Alexandre; Tolentino, Chineyder Corrêa; Souza, Fernanda Rodrigues de; Huss, Juliana Carla da Costa; Zinato, Karolinne de Lourdes

Objective: investigate the effect of GC-1 on tolerance to exercise in rats with experimental hypothyroidism. Materials and methods: hypothyroidism was induced with methimazole sodium and perchlorate treatment. Six groups with eight animals were studied: control group (C), hypothyroid group without treatment (HYPO); hypothyroidism treated with physiological doses of tetraiodothyronine (T4) or 10 times higher (10...

Date: 2017   |   Origin: Oasisbr

Efeitos cardiovasculares da associação do hormônio tireoidiano e do exercício f...

Souza, Fernanda Rodrigues de

Fundação de Amparo a Pesquisa do Estado de Minas Gerais; Introduction: The hyperthyroidism produces hemodynamic changes and cardiac hypertrophy, however, many of their characteristics and effects of its association with physical exercise are not clear. Objective: Evaluating the cardiovascular effects of the association of thyroid hormone and physical exercise in rats. Methods: We used 37 adult male rats weighin...

Date: 2016   |   Origin: Oasisbr

Efeito da leucina na hipertrofia cardíaca e na concentração sérica de creatina ...

Fidale, Thiago Montes; Gonçalves, Alexandre; Lopes, Leandro Teixeira Paranhos; Alves, Poliana Rodrigues; Souza, Fernanda Rodrigues de

A leucina é um regulador do metabolismo proteico in vivo, e existem poucas informações referentes à sua ação na hipertrofia cardíaca induzida pelo hipertireoidismo experimental e sua relação com a creatina quinase sérica. O estudo teve por objetivo verificar a ação da leucina na hipertrofia cardíaca e na concentração sérica de creatina quinase em ratos Wistar em hipertireoidismo. Foram utilizados 20 animais, di...

Date: 2013   |   Origin: Oasisbr

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