Objetivo: analisar as principais afecções neurológicas decorrentes da infecção pelo vírus SARS-CoV-2 (síndrome respiratória aguda grave de coronavírus 2) através de uma revisão integrativa. Metodologia: trata-se de um estudo de revisão integrativa da literatura. Para a seleção dos artigos foram usadas duas bases de dados: PUBMED e Scielo, e estabeleceram-se como critérios de inclusão: estudos de relato de caso ...
SARS-CoV-2 virus, cause of COVID-19 disease, was described at first in Wuhan (China) December 2019, infecting more than 170 million people. During viral infection, innate immune system initially acts with cell signaling leading to the production and release of pro-inflammatory cytokines, mostly characterized by low levels of interferons (IFNs), which stimulate the expression of genes that contribute to the disp...
Obesity is characterized by the excessive accumulation of body fat at a level that compromises the health of individuals and is associated with the development of chronic diseases. The treatment of obesity consists of diet modification, institution of physical activity and pharmacotherapy followed or not by bariatric surgery. Although surgery has shown positive results in terms of weight loss and reversal of co...
Humans developed a symbiotic relationship with their gut microbiota, a complex microbial community made up of bacteria, archaea, protists and viruses, including bacteriophages. The enteric nervous system (SNE) is a gateway to bidirectional communication between the brain and the intestine, mainly through the vagus nerve (VN). Therefore, environmental exposure plays a fundamental role in both the composition and...
Intestinal mucositis is a common complication associated with 5-fluorouracil (5-FU), a chemotherapeutic agent used for cancer treatment. Cashew gum (CG) has been reported as a potent anti-inflammatory agent. In the present study, we aimed to evaluate the e ect of CG extracted from the exudate of Anacardium occidentale L. on experimental intestinal mucositis induced by 5-FU. Swiss mice were randomly divided into...