3 documents found, page 1 of 1
Withanolides from leaves of Nicandra physalodes
Carrero, Diego A. S.; Batista, Pedro H. J.; Souza, Luciana G. S.; Pinto, Francisco C. L.; Vasconcelos, Mayron A. de; Teixeira, Edson H.Five new withanolides, designated as 15-oxo-nicaphysalin B, 6 β ,7 α -dihydroxynicandrenone 10, 24 α ,25 β -dihydroxy-nicandrenone-2 and a mixture of the epimers 17-(1 α /1 β -methylpropanone)- nicandrenone, in addition to six known others, were isolated from the leaf acetone extract from Nicandra physalodes . The complete structures of the five new withanolides, particularly their relative stereochemistries, w...
7-epi-griffonilide, a new lactone from Bauhinia pentandra: complete 1H and 13C ...
Almeida, Macia Cleane Soares de; Souza, Luciana G. S.; Ferreira, Daniele A.; Pinto, Francisco C. L.; Oliveira, Débora R. de; Santiago, Gilvandete M. P.A new lactone, 7-epi-griffonilide (1), and six known compounds, 2, 3a - 3c, 4a and 4b, were isolated from the leaves of Bauhinia pentandra (Fabaceae). The structures elucidation of 1 and 2 were based on detailed 2D NMR techniques and spectral comparison with related compounds, leading to complete assignment of the 1H and 13C NMR spectra.
Biflorin : an o-naphthoquinone of clinical significance
Wisintainer, Gabrielle G. N. S.; Simões, Evelyne R. B.; Lemos, Telma L. G.; Moura, Sidnei; Souza, Luciana G. S.; Fonseca, Aluisio M.Biflorin is an o -naphthoquinone with proven cytotoxic effects on tumor cells showing antimicrobial, antitumor and antimutagenic activities. Biflorin is an isolated compound taken from the roots of the plant Capraria biflora L. (Schrophulariaceae), indigenous of the West Indies and South America, which is located in temperate or tropical areas. This compound has shown to be strongly active against gram- positiv...