2 documents found, page 1 of 1
Carvacrol, (−)-borneol and citral reduce convulsant activity in rodents
Quintans-Júnior, Lucindo José; Guimarães, Adriana Gibara; Araújo, Bruno Eduardo Silva de; Cavalcanti, Sócrates Cabral de HolandaCarvacrol, a monoterpenic phenol present in essential oils of the Labiatae family, has been used through the ages as a source of flavor in food and for medicinal purposes. Borneol is a monoterpene found in several species of Artemisia and Dipterocarpaceae, used for anxiety, pain and anesthesia in traditional Chinese. Citral, a mixture of two geometrical isomers (neral and geranial), is one of the most important...
Bioassay-guided evaluation of central nervous system effects of citronellal in ...
Melo, Mônica Santos de; Souza, Marilia Trindade de Santana; Guimarães, Adriana Gibara; Barreto, Rosana de Souza SiqueiraThe central nervous system (CNS) depressant and anticonvulsant activities of citronellal (CT) were investigated in animal models. The CT in doses of 100, 200 and 400 mg/kg injected by i.p. route in mice caused a significant decrease in the motor activity of animals when compared with the control group. The highest dose of CT significantly reduced the remaining time of the animals on the Rota-rod apparatus up to...