5 documents found, page 1 of 1
Leishmania infantum ecto-nucleoside triphosphate diphosphohydrolase-2 is an apy...
Vasconcellos, Raphael De Souza; Mariotini-Moura, Christiane; Gomes, Rodrigo Saar; Serafim, Tiago Donatelli; Firmino, Rafaela de CássiaVisceral leishmaniasis is an important tropical disease, and Leishmania infantum chagasi (synonym of Leishmania infantum) is the main pathogenic agent of visceral leishmaniasis in the New World. Recently, ecto-nucleoside triphosphate diphosphohydrolases (E-NTPDases) were identified as enablers of infection and virulence factors in many pathogens. Two putative E-NTPDases (∼70 kDa and ∼45 kDa) have been found in ...
Recombinant Leishmania (Leishmania) infantum Ecto-Nucleoside Triphosphate Dipho...
Souza, Ronny Francisco de; Santos, Yaro Luciolo dos; Vasconcellos, Raphael de Souza; Borges-Pereira, Lucas; Almeida, Márcia Rogéria deCanine visceral leishmaniasis is an important public health concern. In the epidemiological context of human visceral leishmaniasis, dogs are considered the main reservoir of Leishmania parasites; therefore, dogs must be epidemiologically monitored constantly in endemic areas. Furthermore, dog to human transmission has been correlated with emerging urbanization and increasing rates of leishmaniasis infection wo...
Expressão Heteróloga, Purificação e Avaliação do uso da E-NTPDase (GDPase) de L...
Souza, Ronny Francisco deFundação de Amparo a Pesquisa do Estado de Minas Gerais; The canine visceral leishmaniasis is an emerging zoonotic disease highly prevalent in tropical countries. Several studies have used recombinant proteins in serological tests for its diagnosis. This work describes the heterologous expression in Escherichia coli BL21-(DE3) pET-21b system of Leishmania major GDPase. The GDPase recombinant protein (rGDPase) w...
Expressão e purificação da proteína recombinante NTPDase2 de Leishmania infantu...
Souza, Ronny Francisco deFundação de Amparo a Pesquisa do Estado de Minas Gerais; In Brazil leishmaniasis are zoonotic diseases character, being transmitted by blood-sucking sand flies of the family Psychodidae. The development of clinical forms: visceral or cutaneous, is closely related to species involved in infection and immune status of the infected individual. The dog is currently the main reservoir of epidemiological importance. ...
Recombinant leishmania (Leishmania) infantum ecto-nucleoside triphosphate dipho...
Souza, Ronny Francisco de; Santos, Yaro Luciolo dos; Vasconcellos, Raphael de Souza; Pereira, Lucas Borges; Caldas, Ivo SantanaCanine visceral leishmaniasis is an important public health concern. In the epidemiological context of human visceral leishmaniasis, dogs are considered the main reservoir of Leishmania parasites; therefore, dogs must be epidemiologically monitored constantly in endemic areas. Furthermore, dog to human transmission has been correlated with emerging urbanization and increasing rates of leishmaniasis infection wo...