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The concurrent occurrence of Leishmania chagasi infection and childhood acute l...

Vasconcelos,Gisele Moledo de; Azevedo-Silva,Fernanda; Thuler,Luiz Claudio dos Santos; Pina,Eugênia Terra Granado; Souza,Celeste S.F.; Calabrese,Katia

Objective: This study investigated the co-existence of Leishmania chagasi infection and childhood leukemia in patients naïve to treatment; this has serious clinical and epidemiological implications. Methods: The seroprevalence of L. chagasi antibodies prior to any treatment was investigated in children with clinical features of acute leukemia. Serological tests were performed in 470 samples drawn from under 14-...

Date: 2014   |   Origin: Oasisbr

Actin-interacting and flagellar proteins in Leishmania spp.: bioinformatics pre...

Diniz,Michely C.; Costa,Marcília P.; Pacheco,Ana C.L.; Kamimura,Michel T.; Silva,Samara C.; Carneiro,Laura D.G.; Sousa,Ana P.L.; Soares,Carlos E.A.

Several motile processes are responsible for the movement of proteins into and within the flagellar membrane, but little is known about the process by which specific proteins (either actin-associated or not) are targeted to protozoan flagellar membranes. Actin is a major cytoskeleton protein, while polymerization and depolymerization of parasite actin and actin-interacting proteins (AIPs) during both processes ...

Date: 2009   |   Origin: Oasisbr

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