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Patients with neuromyelitis optica have a more severe disease than patients wit...
Bichuetti,Denis Bernardi; Oliveira,Enedina Maria Lobato de; Souza,Nilton Amorin de; Tintoré,Mar; Gabbai,Alberto AlainAlthough neuromyelitis optica (NMO) is known to be a more severe disease than relapsing-remitting multiple sclerosis (RRMS), few studies comparing both conditions in a single center have been done.Methods:Comparison of our previously published cohort of 41 NMO patients with 177 RRMS patients followed in the same center, from 1994 to 2007.Results:Mean age of onset was 32.6 for NMO and 30.2 for RRMS (p=0.2062) wi...
Neuromyelitis optica: brain abnormalities in a Brazilian cohort
Bichuetti,Denis Bernardi; Rivero,René Leandro Magalhães; Oliveira,Daniel May; Souza,Nilton Amorin de; Abdala,Nitamar; Oliveira,Enedina Maria LobatoNeuromyelitis optica (NMO) is a demyelinating disease consisting of relapsing-remitting optic neuritis and myelitis with a more severe course than Multiple Sclerosis. Recently, it has been shown that almost 50% of patients with NMO can have brain magnetic resonance imaging (MRI) abnormalities. We report on six Brazilian patients with NMO, fulfilling the 1999 Wingerchuck criteria for this disease, with abnormal ...