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Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA-MeDAL...

Bousquet, J.; Melén, E.; Haahtela, T.; Koppelman, G. H.; Togias, A.; Valenta, R.; Akdis, C. A.; Czarlewski, W.; Rothenberg, M.; Valiulis, A.

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease," coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhiniti...


Rhinitis associated with asthma is distinct from rhinitis alone: The ARIA‐MeDAL...

Bousquet, J.; Melén, E.; Haahtela, T.; Koppelman, G. H.; Togias, A.; Valenta, R.; Akdis, C. A.; Czarlewski, W.; Rothenberg, M.; Valiulis, A.

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease," coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhiniti...


Geolocation with respect to personal privacy for the Allergy Diary app - a MASK...

Samreth, D.; Arnavielle, S.; Ingenrieth, F.; Bedbrook, A.; Onorato, G. L.; Murray, R.; Almeida, R.; Mizani, M. A.; Fonseca, J.; Costa, E.; Malva, João

Background Collecting data on the localization of users is a key issue for the MASK (Mobile Airways Sentinel networK: the Allergy Diary) App. Data anonymization is a method of sanitization for privacy. The European Commission’s Article 29 Working Party stated that geolocation information is personal data. To assess geolocation using the MASK method and to compare two anonymization methods in the MASK database t...


Scale-up studies of the supercritical fluid extraction of triterpenic acids fro...

de Melo, M. M. R.; Domingues, R. M. A.; Sova, M.; Lack, E.; Seidlitz, H.; Lang, F., Jr.; Silvestre, A. J. D.; Silva, C. M.

The supercritical fluid extraction (SFE) of Eucalyptus globulus deciduous bark is investigated, under the context of biorefinery, aiming at the definition of a pathway for the production of enriched extracts in triterpenic acids (TTAs). Scale-up studies are performed, well supported by modeling and by experiments carried out at lab, intermediate and pilot scales (0.5, 5.0 and 80.0 L, respectively). By acknowled...


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