2 documents found, page 1 of 1
The astrocyte α1A-adrenoreceptor is a key component of the neuromodulatory syst...
Wahis, J; Akkaya, C; Kirunda, AM; Mak, A; Zeise, K; Verhaert, J; Gasparyan, H; Hovhannisyan, S; Holt, MGNoradrenaline (norepinephrine) is known to modulate many physiological functions and behaviors. In this study, we tested to what extent astrocytes, a type of glial cell, participate in noradrenergic signaling in mouse primary visual cortex (V1). Astrocytes are essential partners of neurons in the central nervous system. They are central to brain homeostasis, but also dynamically regulate neuronal activity, nota...
Traumatic brain injury promotes neurogenesis at the cost of astrogliogenesis in...
Bielefeld, P; Martirosyan, A; Martín-Suárez, S; Apresyan, A; Meerhoff, GF; Pestana, F; Poovathingal, S; Reijner, N; Koning, W; Clement, RA; Veen, IVdTraumatic brain injury (TBI) can result in long-lasting changes in hippocampal function. The changes induced by TBI on the hippocampus contribute to cognitive deficits. The adult hippocampus harbors neural stem cells (NSCs) that generate neurons (neurogenesis), and astrocytes (astrogliogenesis). While deregulation of hippocampal NSCs and neurogenesis have been observed after TBI, it is not known how TBI may aff...