13 documents found, page 1 of 2
Indeterminate form of Chagas disease: historical, conceptual, clinical, and pro...
Hasslocher-Moreno,Alejandro Marcel; Xavier,Sergio Salles; Saraiva,Roberto Magalhães; Sousa,Andréa Silvestre deAbstract Chagas disease (CD) remains a serious endemic disease in Latin America and a major public health problem. Because of globalization, the disease has spread to non-endemic areas in the northern hemisphere. In the chronic phase of the disease, most patients present with the indeterminate form (IF), characterized by positive serology for Trypanosoma cruzi, absence of clinical findings, and normal findings ...
Temporal changes in the clinical-epidemiological profile of patients with Chaga...
Hasslocher-Moreno,Alejandro Marcel; Saraiva,Roberto Magalhaes; Brasil,Pedro Emmanuel Alvarenga Americano do; Sangenis,Luiz Henrique CondeAbstract INTRODUCTION We aimed to describe the sociodemographic, epidemiological, and clinical characteristics of patients with chronic Chagas disease (CD) at an infectious disease referral center. Changes in patient profiles over time were also evaluated. METHODS This retrospective study included patients with CD from November 1986-December 2019. All patients underwent an evaluation protocol that included soci...
Synergistic Effect of Disease Severity, Anxiety Symptoms and Elderly Age on the...
Figueiredo,José Henrique Cunha; Oliveira,Gláucia Maria Moraes de; Pereira,Basílio Bragança; Figueiredo,Ana Elisa Bastos; Nascimento,Emília MatosAbstract Background: Heart failure (HF) is a multifactorial syndrome with repercussions on quality of life (QoL). Objectives: To investigate the main interacting factors responsible to worsen quality of life of outpatients with HF. Methods: Cross-sectional observational study with 99 patients of both genders, attending a HF outpatient clinic at a university hospital, all with a reduced ejection fraction (<40%) ...
Registro Multicêntrico de Takotsubo (REMUTA) – Aspectos Clínicos, Desfechos Int...
Almeida Junior,Gustavo Luiz Gouvêa de; Mansur Filho,João; Albuquerque,Denilson Campos de; Xavier,Sergio Salles; Pontes,Álvaro; Gouvêa,Elias PimentelResumo Fundamento A síndrome de takotsubo (takotsubo) é uma forma de cardiomiopatia adquirida. Dados nacionais sobre essa condição são escassos. O Registro REMUTA é o primeiro a incluir dados multicêntricos dessa condição no nosso país. Objetivo Descrever as características clínicas, prognóstico, tratamento intra-hospitalar e mortalidade hospitalar e em 1 ano de seguimento. Métodos Estudo observacional, retrosp...
Global Longitudinal Strain Accuracy for Cardiotoxicity Prediction in a Cohort o...
Gripp,Eliza de Almeida; Oliveira,Gabriela Escudini de; Feijó,Luiz Augusto; Garcia,Marcelo Iorio; Xavier,Sergio Salles; Sousa,Andréa Silvestre deAbstract Background: The high cardiotoxicity morbidity and mortality rates associated with the antineoplastic therapy for breast cancer could be reduced with the early use of cardioprotective drugs. However, the low sensitivity of left ventricular ejection fraction limits its use in that preventive strategy. New parameters, such as global longitudinal strain, are being used in the early detection of contractile...
Natriuretic Peptide and Clinical Evaluation in the Diagnosis of Heart Failure H...
Almeida Junior,Gustavo Luiz Gouvêa de; Clausell,Nadine; Garcia,Marcelo Iorio; Esporcatte,Roberto; Rangel,Fernando Oswaldo Dias; Rocha,Ricardo MourilheAbstract Background: Physical examination and B-type natriuretic peptide (BNP) have been used to estimate hemodynamics and tailor therapy of acute decompensated heart failure (ADHF) patients. However, correlation between these parameters and left ventricular filling pressures is controversial. Objective: This study was designed to evaluate the diagnostic accuracy of physical examination, chest radiography (CR) ...
Acurácia do relacionamento probabilístico de registros na identificação de óbit...
Spineti,Pedro Pimenta de Mello; Souza,Andrea Silvestre de; Feijó,Luiz Augusto; Garcia,Marcelo Iorio; Xavier,Sergio SallesResumo O relacionamento probabilístico de registros vem sendo cada vez mais empregado na identificação de desfechos em estudos de coorte. O objetivo deste trabalho foi avaliar a acurácia deste método na identificação de óbitos em uma coorte de 450 pacientes admitidos em um hospital universitário por insuficiência cardíaca descompensada, em um período de seis anos. O estado vital dos membros da coorte foi determ...
Cardiac rehabilitation program in patients with Chagas heart failure: a single-...
Mediano,Mauro Felippe Felix; Mendes,Fernanda de Souza Nogueira Sardinha; Pinto,Vivian Liane Mattos; Silva,Gilberto Marcelo Sperandio daAbstract: INTRODUCTION: The benefit of a cardiac rehabilitation (CR) program for patients with Chagas heart failure (CHF) remains unclear. Therefore, we aimed to investigate the effects of CR for CHF patients. METHODS: A single-arm pilot study, including 12 patients with CHF, was performed. Patients participated in an 8-month physical exercise intervention, comprising aerobic, strength, and stretching exercises...
Does my patient have chronic Chagas disease? Development and temporal validatio...
Brasil,Pedro Emmanuel Alvarenga Americano do; Xavier,Sergio Salles; Holanda,Marcelo Teixeira; Hasslocher-Moreno,Alejandro Marcel; Braga,José UeleresAbstract: INTRODUCTION With the globalization of Chagas disease, unexperienced health care providers may have difficulties in identifying which patients should be examined for this condition. This study aimed to develop and validate a diagnostic clinical prediction model for chronic Chagas disease. METHODS This diagnostic cohort study included consecutive volunteers suspected to have chronic Chagas disease. The...
Atrial Fibrillation in Decompensated Heart Failure: Associated Factors and In-H...
Mendes,Fernanda de Souza Nogueira Sardinha; Atié,Jacob; Garcia,Marcelo Iorio; Gripp,Eliza de Almeida; Sousa,Andréa Silvestre de; Feijó,Luiz AugustoBackground: Studies on atrial fibrillation (AF) in decompensated heart failure (DHF) are scarce in Brazil. Objectives: To determine AF prevalence, its types and associated factors in patients hospitalized due to DHF; to assess their thromboembolic risk profile and anticoagulation rate; and to assess the impact of AF on in-hospital mortality and hospital length of stay. Methods: Retrospective, observational, cro...