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The prevalence of comorbidities in COPD patients, and their impact on health st...

Ställberg, Björn; Teixeira, Pedro Miguel Silva Costa Afonso; Blom, Coert; Lisspers, Karin; Tsiligianni, Ioanna; Jordan, Rachel; Román, Miguel

[Abstract] Chronic obstructive pulmonary disease (COPD) is an important cause of morbidity and mortality with high social and economic costs. The prevalence of COPD has been reported to vary between 6 and 26.1% worldwide.1 COPD has also been associated with a high prevalence of one or more comorbid conditions, which have an impact on health status and mortality.2–5 Although several diseases have been studied as...


Are pharmacological randomised controlled clinical trials relevant to real-life...

Lisspers, Karin; Teixeira, Pedro Miguel Silva Costa Afonso; Blom, Coert; Kocks, Janwillem; Ställberg, Björn; Price, David; Chavannes, Niels

[Excerpt] Introduction: Asthma has a high prevalence worldwide with a high incidence in primary care settings in many countries.1 It is by definition a variable disease with a broad spectrum of clinical phenotypes, in which management and treatment can be difficult.2–8 The aim of asthma treatment is optimal control of the disease, which according to Global Initiative for Asthma (GINA) guidelines implies both symp...


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