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The benefit of EXtending oral antiCOAgulation treatment EXCOA after acute cereb...

Miranda, Bruno; Aaron, Sanjith; Arauz, Antonio; Barinagarrementeria, Fernando; Borhani-Haghighi, Afshin; Carvalho, Marta; Conforto, Adriana B.

Rationale: After a cerebral vein thrombosis, there is an increased risk of further venous thromboembolic events. The optimal duration of anticoagulation after cerebral vein thrombosis is unknown. Aim: To compare efficacy and safety of a policy of short- (3–6 months) versus long-term (12 months) anticoagulation (any type venous thromboembolic events) after cerebral vein thrombosis for the prevention of venous th...


Risk score to predict the outcome of patients with cerebral vein and dural sinu...

Ferro, José; Bacelar-Nicolau, Helena; Rodrigues, Teresa; Bacelar-Nicolau, Leonor; Canhão, Patrícia; Crassard, Isabelle; Bousser, Marie-Germaine

BACKGROUND: Around 15% of patients die or become dependent after cerebral vein and dural sinus thrombosis (CVT). METHOD: We used the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) sample (624 patients, with a median follow-up time of 478 days) to develop a Cox proportional hazards regression model to predict outcome, dichotomised by a modified Rankin Scale score >2. From the model hazar...


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