6 documents found, page 1 of 1
Methylation of the hsa-miR-124, SOX1, TERT, and LMX1A genes as biomarkers for p...
Rogeri, Caroline Domingues; Silveira, Henrique César Santejo; Causin, Rhafaela Lima; Villa, Luisa Lina; Stein, Maíra DegiovaniThe methylation profile of genes in precursor lesions in cervical cancer was characterized to improve screening techniques for high-grade intraepithelial neoplasia.
The Role of Self-Collection by Vaginal Lavage for the Detection of HPV and High...
Kuil, Larissa de Melo; Lorenzi, Adriana Tarla; Stein, Maíra Degiovani; Resende, Júlio César Possati; Antoniazzi, Márcio; Longatto Filho, AdhemarObjective: To compare the results of cervical cytology and high-risk HPV tests using samples obtained using two different collection modalities in a population of Brazilian women: self-collection (vaginal lavage) and cervical Pap testing. Methods: We enrolled 204 women who were aged 18-64 years and had previously obtained abnormal cervical cytology test results; 83.8% of them agreed to participate. The sample w...
A low-cost HPV immunochromatographic assay to detect high-grade cervical intrae...
Mariano, Vânia Sammartino; Lorenzi, Adriana Tarlá; Scapulatempo-Neto, Cristovam; Stein, Maíra Degiovani; Resende, Julio Cesar PossatiObjective To evaluate the reproducibility and accuracy of the HPV16/18-E6 test. Methods The study population was comprised of 448 women with a previously abnormal Pap who were referred to the Barretos Cancer Hospital (Brazil) for diagnosis and treatment. Two cervical samples were collected immediately before colposcopy, one for the hr-HPV-DNA test and cytology and the other for the HPV16/18-E6 test using high-a...
Identification of cervicovaginal flora in liquid based Surepath™: Results of ro...
Stein, Maíra Degiovani; Fregnani, José Humberto T. G.; Scapulatempo, Cristovam; Filho, Adhemar LongattoAim of the study: To evaluate the morphological pattern of cervicovaginal flora elements in liquid based SurePath™ cytology.Material and methods: During the period between May, 2010 and August, 2011, 10.166 gynecological samples preserved in liquid based SurePath were evaluated at Barretos Cancer Hospital, in order to identify cervicovaginal flora.Results: Data showed that Lactobacillus sp were observed in 48.9...
Cervicovaginal cytology in patients undergoing pelvic radiotherapy using the Fo...
Stein, Maíra Degiovani; Fregnani, José Humberto T. G.; Scapulatempo-Neto, Cristovam; Longatto Filho, AdhemarBackgroundEvaluate the performance of the Focalpoint system in identifying and classifying cervical cytology alterations from samples collected from patients treated with Radiotherapy (RT).MethodsThe reproducibility of manual and automated screening by cytotechnologists using the BD Focalpoint GS Imaging System was examined. Samples were collected from May 2010 to August 2011.ResultsA total of 378 treated with ...
Performance and Reproducibility of Gynecologic Cytology Interpretation Using th...
Stein, Maíra Degiovani; Fregnani, José Humberto T. G.; Scapulatempo-Neto, Cristovam; Mafra, Allini; Campacci, Natália; Longatto Filho, AdhemarObjectives: To assess whether automated screening in the cytologic examination of Papanicolaou smear slides results in smaller margins of error than manual screening. Methods: We compared cytotechnologists’ performance and reproducibility of manual and automated screening of 10,165 consecutive cervical cytology slides examined at Barretos Cancer Hospital using the FocalPoint system. Results: In total, 83% of at...