2 documents found, page 1 of 1
cis-bis(N-benzoyl-N0 ,N0 -dibenzylthioureido) platinum(II) : synthesis, molecul...
Correa, Rodrigo de Souza; Oliveira, Katia Mara de; Pérez, Hiram; Stevens, Ana María Plutín; Cairo, Raúl Ramos; Mocelo, Raúl; Castellano, Eduardo ErnestoIn this paper, the title compound was synthesized from N-benzoyl-N′,N′-dibenzylthiourea ligand and potassium tetrachloroplatinate(II), and its interaction with human (HSA) and bovine (BSA) serum albumin was evaluated. Also, the crystal structure was determined from single-crystal X‐ray diffraction, confirming that the platinum atom is coordinated with two chelated N-benzoyl-N′,N′-dibenzylthiourea ligands in a d...
Understanding the conformational changes and molecular structure of furoyl thio...
Cairo, Raúl Ramos; Stevens, Ana María Plutín; Oliveira, Tamires Donizeth de; Batista, Alzir Azevedo; Castellano, Eduardo Ernesto; Duque, Julio1-Acyl thioureas [R1C(O)NHC(S)NR2R3] are shown to display conformational flexibility depending on the degree of substitution at the nitrogen atom. The conformational landscape and structural features for two closely related thioureas having R1=2-furoyl have been studied. The un-substituted 2-furoyl thiourea (I) and its dimethyl analogue, i.e. 1-(2-furoyl)-3,3-dimethyl thiourea (II), have been synthesized and fu...