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Writing 3D In vitro models of human tendon within a biomimetic fibrillar suppor...

Monteiro, Rosa F.; Bakht, Syeda Mahwish; Gómez-Florit, Manuel; Stievani, Fernanda C.; Alves, Ana L. G.; Reis, R. L.; Gomes, Manuela E.

Tendinopathies are poorly understood diseases for which treatment remains challenging. Relevant in vitro models to study human tendon physiology and pathophysiology are therefore highly needed. Here we propose the automated 3D writing of tendon microphysiological systems (MPSs) embedded in a biomimetic fibrillar support platform based on cellulose nanocrystals (CNCs) self-assembly. Tendon decellularized extra...


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