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Basilar artery occlusion management: specialist perspectives from an internatio...

Edwards, Christopher; Drumm, Brian; Siegler, James E.; Schonewille, Wouter J.; Klein, Piers; Huo, Xiaochuan; Chen, Yimin; Abdalkader, Mohamad

Background and purpose: Two early basilar artery occlusion (BAO) randomized controlled trials did not establish the superiority of endovascular thrombectomy (EVT) over medical management. While many providers continue to recommend EVT for acute BAO, perceptions of equipoise in randomizing patients with BAO to EVT versus medical management may differ between clinician specialties. Methods: We conducted an intern...


Global impact of the COVID-19 pandemic on stroke volumes and cerebrovascular ev...

Nguyen, Thanh N.; Qureshi, Muhammad M.; Klein, Piers; Yamagami, Hiroshi; Mikulik, Robert; Czlonkowska, Anna; Abdalkader, Mohamad; Sedova, Petra

Background and objectives: Declines in stroke admission, IV thrombolysis (IVT), and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the effect of the COVID-19 pandemic on the volumes of str...


European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for a...

Berge, Eivind; Whiteley, William; Audebert, Heinrich; De Marchis, Gian Marco; Fonseca, Ana Catarina; Padiglioni, Chiara; Pérez de la Ossa, Natalia

Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to assist physicians in their clinical decisions with regard to intravenous thrombolysis for acute ischaemic stroke. These guidelines were developed based on the ESO standard operating procedure and follo...


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