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The Wearing-Off of OnabotulinumtoxinA in Patients with Chronic Migraine: Experi...

Fernandes, Catarina; Silva, Bruno; Ramos-Lopes, Joana; Luzeiro, Isabel

Introduction: The onabotulinumtoxinA (onabotA) is an injectable preventive treatment of chronic migraine (CM), administered in 12 week’s intervals. Some patients present a wearing-off (WO) effect in the last weeks before the next treatment. The aim of our study was to evaluate the WO phenomen in patients under onabotA treatment and to recognize possible predictive features of the phenomena. Methods: We designed...

Date: 2023   |   Origin: SINAPSE

Acute Generalized Chorea, Dystonia and Brain Calcifications: A Case Report

Ramos-Lopes, Joana; Brás, Ana; Morgadinho, Ana; Moreira, Fradique

Pathological basal ganglia calcification, or Fahr’s Syndrome, can be secondary to a variety of diseases, namely parathyroid disturbances. Movement disorders are common clinical features, in which chorea is seen in less than 20% of cases and dystonia just in 8%. We report the clinical case of a 49-year-old male with a history of thyroidectomy, who was admitted in Emergency Service with acute generalized chorea a...

Date: 2019   |   Origin: Acta Médica Portuguesa

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