19 documents found, page 1 of 2
Transdifferentiation of plasmatocytes to crystal cells in the lymph gland of Dr...
Marcetteau, Julien; Duarte, Patrícia; Leitão, Alexandre B; Sucena, ÉlioUnder homeostatic conditions, haematopoiesis in Drosophila larvae occurs in the lymph gland and sessile haemocyte clusters to produce two functionally and morphologically different cells: plasmatocytes and crystal cells. It is well-established that in the lymph gland both cell types stem from a binary decision of the medullary prohaemocyte precursors. However, in sessile clusters and dorsal vessel, crystal cell...
Evolution of resistance and disease tolerance mechanisms to oral bacterial infe...
Paulo, Tânia F.; Akyaw, Priscilla A.; Paixão, Tiago; Sucena, ÉlioPathogens exert strong selection on hosts that evolve and deploy different defensive strategies, namely minimizing pathogen exposure (avoidance), directly promoting pathogen elimination (resistance) and/or managing the deleterious effects of illness (disease tolerance). However, how the host response partitions across these processes has not been directly tested in a single host–pathogen system, let alone in th...
Wolbachia and host intrinsic reproductive barriers contribute additively to pos...
Cruz, Miguel; Magalhães, sara; Sucena, Élio; Zélé, FloreWolbachia are maternally-inherited bacteria that induce cytoplasmic incompatibility in many arthropod species. However, the ubiquity of this isolation mechanism for host speciation processes remains elusive, as only few studies have examined Wolbachia-induced incompatibilities when host populations are not genetically compatible. Here, we used three populations of two genetically differentiated colour forms of ...
Wolbachia and host intrinsic reproductive barriers contribute additively to pos...
Cruz, Miguel; Magalhaes, S; Sucena, Élio; Zélé, FloreWolbachia are maternally-inherited bacteria that induce cytoplasmic incompatibility in many arthropod species. However, the ubiquity of this isolation mechanism for host speciation processes remains elusive, as only few studies have examined Wolbachia-induced incompatibilities when host populations are not genetically compatible. Here, we used three populations of two genetically differentiated colour forms of ...
Tetranychus urticae mites do not mount an induced immune response against bacteria
Santos-Matos, Gonçalo; Wybouw, Nicky; Martins, Nelson E.; Zélé, Flore; Riga, Maria; Leitão, Alexandre B.; Vontas, John; Grbić, MiodragThe genome of the spider mite Tetranychus urticae, a herbivore, is missing important elements of the canonical Drosophila immune pathways necessary to fight bacterial infections. However, it is not known whether spider mites can mount an immune response and survive bacterial infection. In other chelicerates, bacterial infection elicits a response mediated by immune effectors leading to the survival of infected ...
Diverse Cis-Regulatory Mechanisms Contribute to Expression Evolution of Tandem ...
Baudouin-Gonzalez, Luís; Santos, Marília A.; Tempesta, Camille; Sucena, Élio; Roch, Fernando; Tanaka, KohtaroPairs of duplicated genes generally display a combination of conserved expression patterns inherited from their unduplicated ancestor and newly acquired domains. However, how the cis-regulatory architecture of duplicated loci evolves to produce these expression patterns is poorly understood. We have directly examined the gene-regulatory evolution of two tandem duplicates, the Drosophila Ly6 genes CG9336 and CG9...
Drosophila Adaptation to Viral Infection through Defensive Symbiont Evolution
Paulo, Tânia F.; Nolte, Viola; Schlötterer, Christian; Sucena, Élio; Teixeira, LuisMicrobial symbionts can modulate host interactions with biotic and abiotic factors. Such interactions may affect the evolutionary trajectories of both host and symbiont. Wolbachia protects Drosophila melanogaster against several viral infections and the strength of the protection varies between variants of this endosymbiont. Since Wolbachia is maternally transmitted, its fitness depends on the fitness of its ho...
Genetics of host-parasite interactions: towards a comprehensive dissection of D...
Magalhães, Sara; Sucena, ÉlioOne of the major challenges in evolutionary biology is to unravel the genetic basis of adaptation. This issue has been gaining momentum in recent years with the accelerated development of novel genetic and genomic techniques and resources. In this issue of Molecular Ecology, Cogni et al. (2016) address the genetic basis of resistance to two viruses in Drosophila melanogaster using a panel of recombinant inbred ...
Drosophila melanogaster larvae make nutritional choices that minimize developme...
Rodrigues, Marisa A.; Martins, Nelson E.; Balancé, Lara F.; Broom, Lara N.; Dias, António J.S.; Fernandes, Ana Sofia D.; Rodrigues, Fábio; Sucena, ÉlioOrganisms from slime moulds to humans carefully regulate their macronutrient intake to optimize a wide range of life history characters including survival, stress resistance, and reproductive success. However, life history characters often differ in their response to nutrition, forcing organisms to make foraging decisions while balancing the trade-offs between these effects. To date, we have a limited understan...
Multispecies Analysis of Expression Pattern Diversification in the Recently Exp...
Tanaka, Kohtaro; Diekmann, Yoan; Hazbun, Alexis; Hijazi, Assia; Vreede, Barbara; Roch, Fernando; Sucena, ÉlioGene families often consist of members with diverse expression domains reflecting their functions in a wide variety of tissues. However, how the expression of individual members, and thus their tissue-specific functions, diversified during the course of gene family expansion is not well understood. In this study, we approached this question through the analysis of the duplication history and transcriptional evo...