1 document found, page 1 of 1

Sort by Issue Date
go first page go previous page
go to page: 1
go next page go last page
rss feed search results

Perinatal thymic-derived CD8αβ-expressing γδ T cells are innate IFN-γ producers...

Sumaria, Nital; Fiala, Gina; Inácio, Daniel; Curado Avelar, Marta Maria; Cachucho, Ana; Pinheiro, Rúben; Wiesheu, Robert; Kimura, Shunsuke

The contribution of γδ T cells to immune responses is associated with rapid secretion of interferon-γ (IFN-γ). Here, we show a perinatal thymic wave of innate IFN-γ-producing γδ T cells that express CD8αβ heterodimers and expand in preclinical models of infection and cancer. Optimal CD8αβ+ γδ T cell development is directed by low T cell receptor signaling and through provision of interleukin (IL)-4 and IL-7. Th...

Date: 2024   |   Origin: Repositório da Universidade de Lisboa
More info.
go first page go previous page
go to page: 1
go next page go last page
rss feed search results

1 Results

Queried text

Refine Results

Author





















Date


Document Type


Access rights


Resource