3 documents found, page 1 of 1
Half-sandwich Ru(p-cymene) compounds with diphosphanes: In Vitro and In Vivo ev...
Lenis Rojas, Oscar; Robalo, M. Paula; Tomaz, Ana Isabel; Fernandes, Alexandra; Roma-Rodrigues, Catarina; Gonçalves Teixeira, Ricardo; Marques, FernandaRuthenium(II) complexes are currently considered attractive alternatives to the widely used platinum-based drugs. We present herein the synthesis and characterization of half-sandwich ruthenium compounds formulated as [Ru(p-cymene)(L)Cl]-[CF3SO3] (L = 1,1-bis(methylenediphenylphosphano)ethylene, 1; L = 1,1-bis(diphenylphosphano)ethylene, 2), which were characterized by elemental analysis, mass spectrometry, H-1...
Paternal and maternal mutations in X-STRs: A GHEP-ISFG collaborative study
Pinto, Nádia; Pereira, Vânia; Tomas, Carmen; Loiola, Silvia; Carvalho, Elizeu F.; Modesti, Nidia; Maxzud, Mariana; Marcucci, Valeria; Cano, HortensiaMade available in DSpace on 2020-12-12T01:14:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-05-01; The GHEP-ISFG organized a collaborative study to estimate mutation rates for the markers included in the Investigator Argus X-12 QS kit Qiagen. A total of 16 laboratories gathered data from 1,612 father/mother/daughter trios, which were used to estimate both maternal and paternal mutation rates, when po...
Ru-II(p‑cymene) compounds as effective and selective anticancer candidates with...
Lenis-Rojas, Oscar A.; Robalo, Maria Paula; Tomaz, Ana Isabel; Carvalho, Andreia; Fernandes, Alexandra; Marques, Fernanda; FOLGUEIRA, MONICARuthenium(II) complexes are currently considered a viable alternative to the widely used platinum complexes as efficient anticancer agents. We herein present the synthesis and characterization of half-sandwich ruthenium compounds with the general formula [Ru(p-cymene)(L-N,N)Cl][CF3SO3] (L = 3,6-di-2-pyridyl-1,2,4,5-tetrazine (1) 6,7-dimethyl-2,3-bis(pyridin-2-yl)quinoxaline (2)), which have been synthesized by ...