7 documents found, page 1 of 1
MOEMS-based Brillouin spectrometer for colon tumor detection
Esteves, Bruno Miguel CarpinteiroO cancro colorretal (CRC) é o terceiro mais diagnosticado e o segundo mais mortal a nível global. Apesar da elevada taxa de mortalidade, o CRC pode apresentar uma taxa de sobrevivência superior a 90%, após tratamento, quando a lesão é pequena e local. O diagnóstico precoce é a estratégia mais eficaz para reduzir a mortalidade e o sofrimento, sendo um foco prioritário dos sistemas de saúde. A colonoscopia é o mé...
Raman spectroscopy for classification of neoplastic and non-neoplastic CAM colo...
Esteves, Bruno Miguel Carpinteiro; Pimenta, Sara Filomena Ribeiro; Maciel, Marino Jesus Correia; Costa, Marta Sílvia Freitas; Baltazar, FátimaThis paper demonstrates the potential of Raman spectroscopy for differentiating neoplastic from non-neoplastic colon tumors, obtained with the CAM (chicken chorioallantoic membrane) model. For the CAM model two human cell lines were used to generate two types of tumors, the RKO cell line for neoplastic colon tumors and the NCM460 cell line for non-neoplastic colon tumors. The Raman spectra were acquired with a ...
Non-contact determination of the viscoelastic properties of agar culture media ...
Esteves, Bruno Miguel Carpinteiro; Rocha, A.; Silva, Manuel Fernando Ribeiro; Correia, J. H.; Rodrigues, José Artur OliveiraThis study aimed to investigate the potential of Brillouin spectroscopy as a non-contact and real-time tool for measuring the viscoelastic properties of agar culture media and using them to determine the percentages of their different components. The Brillouin spectrum of media samples with varying concentrations of different components was successfully acquired. A custom-designed refractometer was employed for...
Non-contact optical analysis of the viscoelastic properties for food quality us...
Esteves, Bruno Miguel Carpinteiro; Rodrigues, José Artur Oliveira; Silva, Manuel Fernando Ribeiro; Maciel, Marino Jesus Correia; Correia, J. H.Brillouin spectroscopy probes the viscoelastic properties of materials by observing the scattered light spectrum from a laser source incident on a given sample. The peak contained in the Brillouin scattering region of the spectrum can be directly correlated to the storage and loss modulus, providing a complex analysis of the physical properties of the study subject (Figure1a) [1]. For the food industry, where t...
Flexible and reduced-size neural probe using a photosensitive polyimide
Freitas, João Rui Martins; Freitas, Ruben Brandão; Esteves, Bruno Miguel Carpinteiro; Santos, Diogo Juvandes Freitas; Maciel, Marino Jesus CorreiaThe understanding of the human brain function is one of the main challenges of modern science, as it comprises the study of an extremely complex organ. The majority of neural interfaces to study the brain rely on non-flexible and relatively thick structures, which do not adapt to the plastic nature of the brain, damaging the tissue and compromising data acquisition [1, 2]. This research presents the fabrication...
Detection of defects on displays based on microscopic and optical coherence tom...
Pereira, Hugo Martins; Freitas, Ruben Brandão; Esteves, Bruno Miguel Carpinteiro; Santos, C. P.; Carvalho, Pedro; Compadrinho, Paulo; Rodrigues, Carlos[Excerpt] Introduction The use of displays in control car panels, smartphones, notebooks and LCD TVs has increased in the last decade. The large-scale manufacturing of new products emphasizes the need for fault detection at an early stage in the assembly process to detect the presence of scratches and particles. Therefore, fast, reliable and efficient displays inspection equipment is essential in order to reduc...
Fabrico e caracterização de um fotodetetor para a integração numa sonda neurona...
Esteves, Bruno Miguel CarpinteiroO ser humano distingue-se dos outros seres vivos por uma ímpar capacidade intelectual. O funcionamento do cérebro foi, desde sempre, um dos grandes focos do estudo científico, e o desenvolvimento tecnológico tem vindo a fornecer ferramentas inovadoras para o estudo do mesmo. O desenvolvimento das tecnologias de manipulação de micro-organismos criou as condições necessárias para o aparecimento da optogenética, c...