Encontrado 1 documento, a visualizar página 1 de 1
Ordenado por
Data
ir para a página:
1
The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in...
de Oliveira, Rita Machado; Vicente Miranda, Hugo; Francelle, Laetitia; Pinho, Raquel; Szegö, Éva M.; Martinho, Renato; Munari, FrancescaSirtuin genes have been associated with aging and are known to affect multiple cellular pathways. Sirtuin 2 was previously shown to modulate proteotoxicity associated with age-associated neurodegenerative disorders such as Alzheimer and Parkinson disease (PD). However, the precise molecular mechanisms involved remain unclear. Here, we provide mechanistic insight into the interplay between sirtuin 2 and α-synucl...
Data: 2017
|
Origem: Repositório Científico do Instituto Nacional de Saúde