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Tumor cardiaco en un paciente de mediana edad con enfermedad coronaria : una ra...
Silva, Ricardo P.; Távora, Fábio; Mont’Alverne Filho, José Ronaldo; Rocha, Marilena G.; Silva, Geraldo B. Silva,We describe a rare association between cardiac tumor and coronary disease. A 42 years old male was admitted with complaints of dyspnea. The physical examination was unremarkable. The electrocardiogram showed sinus rhythm, with right bundle block and ventricular anterior wall repolarization abnormality. The echocardiogram showed a structure with increased echogenicity inside the left atrium, compatible with card...
Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats
Macedo, Francisco Yuri Bulcao; Baltazar, Fátima; Almeida, Paulo Roberto Carvalho; Távora, Fábio; Ferreira, Francisco Valdeci; Schmitt, Fernando C.Purpose Hemorrhagic cystitis (HC) is a limiting side effect of chemotherapy with ifosfamide (IFS). In this study, we investigated the participation of cyclooxygenase-2 (COX-2) upon ifosfamide-induced HC. Methods Male Wistar rats (150-200 g; six rats per group) were treated with saline, IFS (400 mg/kg, i.p.) and analyzed by changes in bladder wet weight, macroscopic and microscopic parameters, and COX-2 expressi...