14 documents found, page 1 of 2

Evaluation of genotoxic and cytotoxic effects of anorectic drugs in lymphocytes...

Obesity is a major public health concern nowadays, as the risk of developing cancer and other chronic diseases has increased considerably in this population. Using in vitro tests (Comet Assay and Micronucleus Test), we evaluated whether lymphocytes from obese individuals (BMI: 40-62 kg / m2) are sensitive to genotoxic and cytotoxic damage when exposed to anorexigenics sibutramine, femproporex and phytotherapics...

Dyslipidemia rather than Type 2 Diabetes Mellitus or Chronic Periodontitis Affe...

Made available in DSpace on 2018-12-11T17:14:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; A high percentage of type 2 diabetes mellitus (T2D) patients are also affected by dyslipidemia and chronic periodontitis (CP), but no studies have determined the gene expression in patients that are simultaneously affected by all three diseases. We investigated the systemic expression of immune-related ...

Nanocellulose-collagen-apatite composite associated with osteogenic growth pept...

Made available in DSpace on 2018-12-11T17:32:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-10-01; Despite advances in the field of biomaterials for bone repair/regeneration, some challenges for developing an ideal bone substitute need to be overcome. Herein, this study synthesized and evaluated in vitro a nanocomposite based on bacterial cellulose (BC), collagen (COL), apatite (Ap) and osteogenic gr...

Expression profile of genes potentially associated with adequate glycemic contr...

Made available in DSpace on 2018-12-11T17:33:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Despite increasing research in type 2 diabetes mellitus (T2D), there are few studies showing the impact of the poor glycemic control on biological processes occurring in T2D. In order to identify potential genes related to poorly/well-controlled patients with T2D, our strategy of investigation included ...

Cytotoxicity and genotoxicity of silver nanoparticles of different sizes in CHO...

Galanthamine decreases genotoxicity and cell death induced by β-amyloid peptide...

Cyto- and genotoxic effects of metallic nanoparticles in untransformed human fi...

AXIN2 polymorphisms, the β-catenin destruction complex expression profile and b...

Evaluation of the toxic activity of anorectic diethylpropion in Chinese hamster...

Detection of human mammaglobin A mRNA in peripheral blood of breast cancer pati...