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Isolation, optimization of production and structure-activity relationship studi...
Wijeratne, E.M. Kithsiri; Carbonezi, Carlos A. [UNESP]; Takahashi, Jacqueline A.; Seliga, Christopher J.; Turbyville, Thomas J.; Pierson, Elizabeth E.Made available in DSpace on 2022-04-29T08:47:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2004-01-01; Southwest Ctr. for Nat. Prod. Res. Office of Arid Lands Studies University of Arizona, 250 E. Valencia Road, Tucson, AZ 85706-6800; Instituto de Quimica Universidade Estadual Paulista, CP. 335, 14800-90 Araraquara, SP; Departmento de Quimica Universidade Federal de Minas Gerais, Belo Horizonte; Div. of ...
Síntese de 2-( 2- piridil) quinolinas promovida por micro- ondas e suas ativida...
Borel, Carmindo R.; Barbosa, Luiz C. A.; Maltha, Célia R. A.; Fernandes, Sergio A.; Santos, Larissa B.; Takahashi, Jacqueline A.In this work a series of 2-(2- pyridyl)quinolines were prepared via a Povarov reaction between anilines, 2-pyridinocarbadehyde and ethyl vinyl ether under microwaves heating conditions. The optimized conditions herein reported allowed the preparation of several pyridylquinolines in yields in the range of 30-83%, some of them not previously accessible by this multicomponent process. The reported methodology has ...
Thiobarbiturates as potential antifungal agents to control human infections cau...
Shabeer, Muhammad; Barbosa, Luiz C. A.; Karak, Milandip; Coelho, Amanda C. S.; Takahashi, Jacqueline A.Hospitalized patients can suffer from Candida and Crytptococcus infections, aggravating underlying health conditions. Due to the development of drug-resistant microorganisms, we report here on the potential of some arylidene-thiobarbiturate to control five Candida spp. and one Cryptococcus species of medical interest. Initially, a bismuth nitrate catalyzed Knoevenagel condensation with thiobarbituric acid and a...
Anti-inflammatory, antimicrobial and acetylcholinesterase inhibitory activities...
Moreira, Maria Eliza C.; Sousa, Grasiely F. de; Aguilar, Mariana G. de; Dias, Danielle F.; Takahashi, Jacqueline A.; Vieira Filho, Sidney A.The new pentacyclic triterpenoids friedel-1-en-3,16-dione (1), 1α,29-dihydroxyfriedelan-3-one (2) and 16β,28,29-trihydroxyfriedelan-3-one (3) were isolated from Maytenus robusta branches in addition to the known, but new for this species, triterpenoid 12α,29-dihydroxyfriedelan-3-one (4). The structures and stereochemistry of the novel triterpenoids were established by IR, 1D/2D NMR and HR-APCIMS spectral data. ...
Bismuth(III) complexes with 2-acetylpyridine- and 2-benzoylpyridine-derived hyd...
Piló, Elisa D. L.; Ferreira, Isabella P.; Recio-Despaigne, Angel A.; Silva, Jeferson G. Da; Ramos, Jonas P.; Marques, Lucas B.; Prazeres, Pedro H. D. M.Complexes [Bi(2AcPh)Cl2]·0.5H2O (1), [Bi(2AcpClPh)Cl2] (2), [Bi(2AcpNO2Ph)Cl2] (3), [Bi(2AcpOHPh)Cl2]·2H2O (4), [Bi(H2BzPh)Cl3]·2H2O (5), [Bi(H2BzpClPh)Cl3] (6), [Bi(2BzpNO2Ph)Cl2]·2H2O (7) and [Bi(H2BzpOHPh)Cl3]·2H2O (8) were obtained with 2-acetylpyridine phenylhydrazone (H2AcPh), its -para-chloro-phenyl- (H2AcpClPh), -para-nitro-phenyl (H2AcpNO2Ph) and -para-hydroxy-phenyl (H2AcpOHPh) derivatives, as well as...