6 documents found, page 1 of 1
Diabetes and cancer: a short review for internists
Talaulicar, MadhucarThe risk of developing a range of cancers is moderately increased in type 1 and type 2 diabetes. Obesity, insulin resistance, hyperinsulinemia, and diabetes therapy with insulin, insulin analogues and sulfonylureas may be responsible for this fact. Metformin seems to have a protective effect. We examined all these aspects, and believe that the current aetiopathogenic link among diabetes, diabetes treatment and ...
Importance of postprandial hyperglicemia to controlling diabetes
Talaulicar, MadhucarMany studies have demonstrated a strong relationship between postprandial hyperglycaemia and the development and progression of diabetes related macrovascular diseases, retinopathy, nephropathy and neuropathy. Therefore, therapies targeting elevated after meals glucose seem to be beneficial, although this has not yet been confirmed by randomized controlled trials. The International Diabetes Federation recommend...
Overweight and obesity: a concise review for clinicians
Talaulicar, MadhucarOverweight and obesity continue to rise being highly prevalent throughout the world, and are related to an unbalance between energy intake and output. Genetic, endocrine, neuroendocrine, behavioral and environmental factors play an important role in their etiopathogenesis. The diagnosis is made based on the body mass index and waist circumference. The prevention and treatment are necessary, since an excessive m...
Postmenopausal osteoporosis: clinical aspects
Talaulicar, MadhucarPostmenopausal osteoporosis is a highly prevalent worldwide skeletal disease. It is characterized by low bone mass, leading to extensive bone fragility. Osteoporosis diagnosis is made on the basis of bone mineral density (BMD) by dual-energy x-ray absorptiometry (DXA). The major complications are fractures. The prevention and treatment of osteoporosis are aimed at reducing substantially the fractures. Calcium a...
Incretin and its use in the treatment of type 2 diabetes mellitus
Talaulicar, MadhucarOral glucose administration results in more insulin release than intravenous injection of the same amount of glucose. This phenomenon has been designated as the “incretin effect”. This effect is caused by the gastrointestinal peptides “gastric inhibitory polypeptide” (GIP) and “glucagon-like peptide-1” (GLP-1). These incretin hormones are responsible for the major part of postprandial insulin secretion. Prepara...
Systemic aortoarteritis: a case review
Talaulicar, MadhucarSystemic aortoarteritis of adults is an uncommon inflammatory disease of uncertain aetiopathogenesis, involving the aorta, pulmonary and temporal arteries as well as their branches.This article analyses the case of a 71-year-old man, a native of India, with symptoms suggestive of an inflammatory or consumptive disease. Positron emission tomography led to the diagnosis, demonstrating diffuse abnormal fluorine-18...