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Experience of a Portuguese Center: Effectiveness of Direct-Acting Antiviral The...

Falcão, Fátima; Lopes, Carla; Viegas, Erica; Perez, Rita; Aldir, Isabel; Farinha, Helena; Carvalho, António; Mirco, Ana; Marques, Susana

Introduction: In late 2014, Portugal implemented a national program for the treatment of patients with chronic hepatitis C with directacting antiviral agents. This program has made Portugal one of the first European countries to implement a structured measure of treatment to eliminate this serious public health problem. The aim of this study was to assess the effectiveness of direct-acting antiviral therapy in ...

Date: 2019   |   Origin: Acta Médica Portuguesa

Impact of early surgery and immunosuppression on Crohn's disease disabling outc...

Magro, Fernando; Dias, Cláudia C.; Coelho, Rosa; Santos, Paula M.; Fernandes, Samuel; Caetano, Cidalina; Rodrigues, Angela; Portela, Francisco

Background and Aims: The definition of early therapeutic strategies to control Crohn's disease aggressiveness and prevent recurrence is key to improve clinical practice. This study explores the impact of early surgery and immunosuppression onset in the occurrence of disabling outcomes. Methods: This was a multicentric and retrospective study with 754 patients with Crohn's disease, who were stratified according ...


Development and validation of risk matrices for Crohn's Disease outcomes in pat...

Dias, Cláudia Camila; Rodrigues, Pedro Pereira; Coelho, Rosa; Santos, Paula Moura; Fernandes, Samuel; Lago, Paula; Caetano, Cidalina; Rodrigues, Angela

Introduction: The establishment of prognostic models for Crohn's disease [CD] is highly desirable, as they have the potential to guide physicians in the decision-making process concerning therapeutic choices, thus improving patients' health and quality of life. Our aim was to derive models for disabling CD and reoperation based solely on clinical/demographic data. Methods: A multicentric and retrospectively enr...


The who-when-why triangle of complementary and alternative medicine use among P...

Portela, Francisco; Dias, Camila C.; Caldeira, Paulo; Cravo, Marilia; Deus, João; Gonçalves, Raquel; Lago, Paula; Morna, Henrique; Peixe, Paula

Background: The use of complementary and alternative medicines is increasing among chronic patients, particularly those afflicted with inflammatory bowel diseases. Aim: This study aimed to address the prevalence of complementary and alternative medicines use among Portuguese inflammatory bowel diseases' patients. Methods: Patients were invited to fill an anonymous questionnaire concerning the use of complementa...


Portuguese Consensus on the Diagnosis, Prevention and Treatment of Anaemia in I...

Magro, Fernando; Ramos, Jaime; Correia, Luís; Lago, Paula; Peixe, Paula; Gonçalves, Ana Rita; Rodrigues, Ângela; Vieira, Catarina; Ferreira, Daniela

Introduction: Anaemia can be considered the most common extra-intestinal manifestation in inflammatory bowel disease. Nevertheless, anaemia is often under-diagnosed and under-treated both in adults and children with inflammatory bowel disease. Herein, we report the consensus statements on the management of anaemia in inflammatory bowel disease developed by the Portuguese Working Group on Inflammatory Bowel Dise...

Date: 2016   |   Origin: Acta Médica Portuguesa

Strategic consensus for the integrated management of hepatitis C in Portugal

Leite, Ricardo Baptista; Universidade Católica Portuguesa; Lopes, Henrique ; Comissão Setorial da Qualidade em Saúde; Peixe, Paula; Marinho, Rui Tato

In May 2013, the Global Commission on Drug Policy released a report on the Hidden Epidemic of Hepatitis C, which contains a set of recommendations to draw the attention of the public and governments to what the World Health Organization considers to be a real viral time bomb. In fact, Chronic Hepatitis C is a disease that affects 170 million people worldwide, infecting almost 4 million people and causing 350,00...

Date: 2014   |   Origin: Open Books - UCEditora

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