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Does salinity variation increase synergistic effects of triclosan and carbon na...

De Marchi, Lucia; Freitas, Rosa; Oliva, Matteo; Cuccaro, Alessia; Manzini, Chiara; Tardelli, Federica; Andrade, Madalena; Costa, Marcelo; Leite, Carla

The use of carbon nanotubes (CNTs) is rapidly increasing and several scientific studies have addressed their toxicological properties. However, only a very small number of publications have deal with the interaction between CNTs and other molecules. Triclosan (TCS) is an antibacterial agent used in personal care and household products. Commonly detected in aquatic ecosystems, there is a strong evidence that aqu...


Soluble esterases as biomarkers of neurotoxic compounds in the widespread serpu...

Casu, Valentina; Tardelli, Federica; De Marchi, Lucia; Monni, Gianfranca; Cuccaro, Alessia; Oliva, Matteo; Freitas, Rosa; Pretti, Carlo

The characterization of soluble cholinesterases (ChEs) together with carboxylesterases (CEs) in Ficopomatus enigmaticus as suitable biomarkers of neurotoxicity was the main aim of this study. ChEs of F. enigmaticus were characterized considering enzymatic activity, substrate affinity (acetyl-, butyryl-, propionylthiocholine), kinetic parameters (Km and Vmax) and in vitro response to model inhibitors (eserine he...


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