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Molecular and cognitive signatures of ageing partially restored through synthet...
Lemaitre, P; Tareen, SH; Pasciuto, E; Mascali, L; Martirosyan, A; Callaerts-Vegh, Z; Poovathingal, S; Dooley, J; Holt, MG; Yshii, L; Liston, ACognitive decline is a common pathological outcome during aging, with an ill-defined molecular and cellular basis. In recent years, the concept of inflammaging, defined as a low-grade inflammation increasing with age, has emerged. Infiltrating T cells accumulate in the brain with age and may contribute to the amplification of inflammatory cascades and disruptions to the neurogenic niche observed with age. Recen...
Date: 2023
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Origin: Repositório Aberto da Universidade do Porto