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A novel molecular mechanism to explain mutations of the HCV protease associated...
Nazario de Moraes, Leonardo [UNESP]; Tommasini Grotto, Rejane Maria [UNESP]; Targino Valente, Guilherme [UNESP]; de Carvalho Sampaio, Heloisa [UNESP]Made available in DSpace on 2020-12-12T00:56:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01; NS3 is an important therapeutic target for direct-acting antiviral (DAA) drugs. However, many patients treated with DAAs have unsustained virologic response (UVR) due to the high mutation rate of HCV. The aim of this work was to shed some light on the puzzling molecular mechanisms of the virus's of pati...
Date: 2020
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Origin: Oasisbr